{"cross_mech":[],"family":{"alphafold_models":240,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This is a family of short ~14 kDa proteins from Psuedomonas. The structure of UniProtKB:Q9HY15 a secreted protein has been solved and deposited as PDB:3npd. It comprises one structural domain with five beta-strands and five alpha-helices. Various comparative structural prediction methods plus its genomic location point to the protein forming a functional dimer with its adjacent genomic partner, UniProtKB:Q9HY14, in [pfam:PF12843]. Together these might be regulated by the other product from the PotABCD operon, namely the putrescine-binding periplasmic protein UniProtKB:Q9HY16. which has been implicated in quorum-sensing. QSregVF is certainly up-regulated in quorum-sensing, and is predicted to be a virulence factor [[cite:PUB00075641]].","domain_architectures":1,"interpro_id":"IPR025203","known_evidence_count":null,"matches":432,"name":"Putative quorum-sensing-regulated virulence factor","partial_evidence_count":null,"pfam_id":"PF13652","proteins":432,"proteomes":430,"short_name":"QSregVF","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13652","structures":1,"taxa":489,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF13652.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":240,"domain_architectures":1,"matches":432,"proteins":432,"proteomes":430,"structures":1,"taxa":489},"curation_status":"SEEDED","description":"This is a family of short ~14 kDa proteins from Psuedomonas. The structure of UniProtKB:Q9HY15 a secreted protein has been solved and deposited as PDB:3npd. It comprises one structural domain with five beta-strands and five alpha-helices. Various comparative structural prediction methods plus its genomic location point to the protein forming a functional dimer with its adjacent genomic partner, UniProtKB:Q9HY14, in [pfam:PF12843]. Together these might be regulated by the other product from the PotABCD operon, namely the putrescine-binding periplasmic protein UniProtKB:Q9HY16. which has been implicated in quorum-sensing. QSregVF is certainly up-regulated in quorum-sensing, and is predicted to be a virulence factor [[cite:PUB00075641]].","id":"Pfam:PF13652","interpro_id":"InterPro:IPR025203","name":"Putative quorum-sensing-regulated virulence factor","pfam_id":"PF13652","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"QSregVF","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13652"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF13652.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"1b0118ad7f3beaaa2ffafe059435de43319cf41fe68f0455d32082e11ff8ca1e"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF13652","short_name":"QSregVF","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}