{"cross_mech":[],"family":{"alphafold_models":1795,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family includes Wadjet protein JetB, a component of anti plasmid transformation system Wadjet type I, composed of JetA, JetB, JetC and JetD. Expression of Wadjet type I in B.subtilis (strain BEST7003) reduces the transformation efficiency of plasmid pHCMC05 [[cite:PUB00097806]]. The Wadjet proteins JetA, JetB, and JetC show sequence similarity to subunits of the bacterial condensin complex MukBEF, a member of the SMCs complex superfamily. The overall structure of JetB and its interaction with JetA is very similar to that of MukE, and the overall positioning of the JetB dimer with respect to JetA is also similar to the MukF-MukE complex [[cite:PUB00163953]]. JetB is composed of two winged helix domains.","domain_architectures":2,"interpro_id":"IPR025449","known_evidence_count":null,"matches":2811,"name":"Wadjet protein JetB","partial_evidence_count":null,"pfam_id":"PF13835","proteins":2811,"proteomes":2611,"short_name":"JetB","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13835","structures":11,"taxa":4161,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF13835.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1795,"domain_architectures":2,"matches":2811,"proteins":2811,"proteomes":2611,"structures":11,"taxa":4161},"curation_status":"SEEDED","description":"This family includes Wadjet protein JetB, a component of anti plasmid transformation system Wadjet type I, composed of JetA, JetB, JetC and JetD. Expression of Wadjet type I in B.subtilis (strain BEST7003) reduces the transformation efficiency of plasmid pHCMC05 [[cite:PUB00097806]]. The Wadjet proteins JetA, JetB, and JetC show sequence similarity to subunits of the bacterial condensin complex MukBEF, a member of the SMCs complex superfamily. The overall structure of JetB and its interaction with JetA is very similar to that of MukE, and the overall positioning of the JetB dimer with respect to JetA is also similar to the MukF-MukE complex [[cite:PUB00163953]]. JetB is composed of two winged helix domains.","id":"Pfam:PF13835","interpro_id":"InterPro:IPR025449","name":"Wadjet protein JetB","pfam_id":"PF13835","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"JetB","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13835"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF13835.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"289c9a392b44624d6b11030417f2d4301c49d15b0155331e3c2a55ccfe2a67ab"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacillus cereus (strain Q1)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/jetb-pf13835.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF13835","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/jetb-pf13835.yaml"}],"pfam_ids":["PF13835"],"protein_name":"Wadjet protein JetB","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MQNVSEREREEMGIVVNYLFSHNFLLKEFEREKYHLAVRNKDIIKQYLQVIGWDFIVDEKHGCIVIVSPHYEHRLKLKKDETIWLLVLRLIYEEKRSALSISQYPFTTLQEIKGKYETFRLPFVSKTKLRELVQIGKQNQLLRPIDNDIESDDCRFQLFHSCIHVLQQGDLNVLYEKIKSYSEGGDHSEMDEETTIN","sequence_length":197,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"8e6251b52c31183b39af46db30db7b17baa113582f4c6cd18f64c899dd2e63dd","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/B9IS84.json","taxon_id":"361100","uniprot_accession":"B9IS84","uniprot_release":"2026_03"}],"pfam_id":"PF13835","short_name":"JetB","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}