{"cross_mech":[],"family":{"alphafold_models":1112,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.","domain_architectures":13,"interpro_id":"IPR025259","known_evidence_count":null,"matches":1251,"name":"Coiled-coil domain-containing protein 34","partial_evidence_count":null,"pfam_id":"PF13904","proteins":1248,"proteomes":975,"short_name":"CCDC34","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13904","structures":0,"taxa":3193,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF13904.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1112,"domain_architectures":13,"matches":1251,"proteins":1248,"proteomes":975,"structures":0,"taxa":3193},"curation_status":"SEEDED","description":"This family is found in eukaryotes; it has several conserved tryptophan residues. The function is not known.","id":"Pfam:PF13904","interpro_id":"InterPro:IPR025259","name":"Coiled-coil domain-containing protein 34","pfam_id":"PF13904","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"CCDC34","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF13904"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF13904.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"f0078bbe33fdf520694ebbb40823f97ab05183898ea1409df8b983f5a44353b6"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/coiled-coil-domain-containing-protein-34-181-ipr025259.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR025259","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/coiled-coil-domain-containing-protein-34-181-ipr025259.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/ccdc34-pf13904.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF13904","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/ccdc34-pf13904.yaml"}],"pfam_ids":["PF13904"],"protein_name":"Coiled-coil domain-containing protein 34","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MRAAGPWRAASPAPCTRYLARCKPGFRPSSSFVVDLLVDSGDPGLEDVALTECLSPPSLSCSNSTLSLLSPLGHQSFPFGADDSEGEDEEALDEDARESESKVESLEGIEFQQRSSCEVESQDKQEKLVLLQHGSLTPWEMWFVGKEKEERGRLQQKFLEELNQQIEKRKEMEEREKRKIIAEVKHKEWVQKKNKQERKEREQKINKEMEEKEAKKREKEHLQEKAKEKYQEWLKKKKAEEYEKKKKEKEKEKQRQAELQEKKEIAEKKFKEWLENAKNKPRPAAKSYGYSSGKLTGFYSGNSYPEPTFYNPIPWKPIHMPPPKEAKSGPGKKSKRHAASQPLPSSSLAVHNAKSSLCLGALCRGQR","sequence_length":367,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"f307eb6ce742886cd2eb4109b6d92eecf6448cfe59f5786b8f1b6d4ab1e9a9cf","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q3UI66.json","taxon_id":"10090","uniprot_accession":"Q3UI66","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/coiled-coil-domain-containing-protein-34-181-ipr025259.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR025259","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/coiled-coil-domain-containing-protein-34-181-ipr025259.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/ccdc34-pf13904.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF13904","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/ccdc34-pf13904.yaml"}],"pfam_ids":["PF13904"],"protein_name":"Coiled-coil domain-containing protein 34","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MWAAGRWGPTFPSSYAGFSADCRPRSRPSSDSCSVPMTGARGQGLEVVRSPSPPLPLSCSNSTRSLLSPLGHQSFQFDEDDGDGEDEEDVDDEEDVDEDAHDSEAKVASLRGMELQGCASTQVESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREKRKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKPRPAAKSYGYANGKLTGFYSGNSYPEPAFYNPIPWKPIHMPPPKEAKDLSGRKSKRPVISQPHKSSSLVIHKARSNLCLGTLCRIQR","sequence_length":373,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"827e89a8917bc3b5799fdf29b009c3318dad654b042d35a8a934eb4677daf2a9","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q96HJ3.json","taxon_id":"9606","uniprot_accession":"Q96HJ3","uniprot_release":"2026_03"}],"pfam_id":"PF13904","short_name":"CCDC34","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}
