{"cross_mech":[],"family":{"alphafold_models":12753,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents the Pathogen and abiotic stress response, cadmium tolerance, disordered region-containing (PADRE) domain, which is specifically found in plants. PADRE typically occurs in small single-domain proteins with a bipartite architecture. PADRE contains conserved sequence motifs at the N-terminal, and its C-terminal includes an intrinsically disordered region with multiple phosphorylation sites. This domain is associated with plant defense upon diverse stress stimulus and has a role in disease resistance to fungi [[cite:PUB00098607]].","domain_architectures":134,"interpro_id":"IPR025322","known_evidence_count":null,"matches":15711,"name":"PADRE domain","partial_evidence_count":null,"pfam_id":"PF14009","proteins":15658,"proteomes":381,"short_name":"PADRE","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14009","structures":0,"taxa":1078,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF14009.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":12753,"domain_architectures":134,"matches":15711,"proteins":15658,"proteomes":381,"structures":0,"taxa":1078},"curation_status":"SEEDED","description":"This entry represents the Pathogen and abiotic stress response, cadmium tolerance, disordered region-containing (PADRE) domain, which is specifically found in plants. PADRE typically occurs in small single-domain proteins with a bipartite architecture. PADRE contains conserved sequence motifs at the N-terminal, and its C-terminal includes an intrinsically disordered region with multiple phosphorylation sites. This domain is associated with plant defense upon diverse stress stimulus and has a role in disease resistance to fungi [[cite:PUB00098607]].","id":"Pfam:PF14009","interpro_id":"InterPro:IPR025322","name":"PADRE domain","pfam_id":"PF14009","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"PADRE","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14009"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF14009.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"80c4e770f1be193d4ceec7e34e59302d9ecd50455e7d7c720aab118d52a9965e"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Arabidopsis thaliana","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/padre-pf14009.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF14009","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/padre-pf14009.yaml"}],"pfam_ids":["PF14009"],"protein_name":"Uncharacterized protein At1g66480","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGNSITVKRKRAKVMKIDGETFRIKTPVTAREVTADYPGYVLLDSQAVKHFGVRSKPLEPNQTLKPKKTYFLVELPKLPPETTAVDTENKLPYRRVMSGIHVGAKERLDMLMLSRRTVSDVTIGRSDGGDGFGPELGPGHTSVRLRLPRSQITKLMEENNNDASAIAEKILGIYMERSGELGGGRGGVDGRRELGSGEIKAREKQVSFAGEGGRELPVLWSRSGK","sequence_length":225,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"be760ed1ecae12c581f127a307cb8f718e95b1d2e735df0142f3b6c3f77dd059","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q6NLC8.json","taxon_id":"3702","uniprot_accession":"Q6NLC8","uniprot_release":"2026_03"}],"pfam_id":"PF14009","short_name":"PADRE","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}