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It is involved in maintenance of mitochondrial homeostasis and cell survival [[cite:PUB00093681]].","domain_architectures":13,"interpro_id":"IPR028043","known_evidence_count":null,"matches":972,"name":"ATPase PAAT-like","partial_evidence_count":null,"pfam_id":"PF14958","proteins":961,"proteomes":708,"short_name":"PAAT-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14958","structures":0,"taxa":2617,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF14958.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":810,"domain_architectures":13,"matches":972,"proteins":961,"proteomes":708,"structures":0,"taxa":2617},"curation_status":"SEEDED","description":"This family is found in eukaryotes. It represents the ATPase protein associated with ABC transporters (PAAT) and related proteins. PAAT is formed of a nucleotide-binding domain (NBD)-like domain and a signal for intramitochondrial sorting. PAAT interacts with the mitochondrial inner membrane ABC proteins: ABCB7, ABCB8 and ABCB10. It is involved in maintenance of mitochondrial homeostasis and cell survival [[cite:PUB00093681]].","id":"Pfam:PF14958","interpro_id":"InterPro:IPR028043","name":"ATPase PAAT-like","pfam_id":"PF14958","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"PAAT-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14958"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF14958.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"f0b647d40968714d9df964335150592b2508ae158026134bb5160d2de8d035cb"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/paat-like-pf14958.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF14958","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/paat-like-pf14958.yaml"}],"pfam_ids":["PF14958"],"protein_name":"ATPase PAAT","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"METAIEDAGLDRGPTLTSSWDAACGALTQSLFLTRTGPRAQDLDFEQLLEPPAPSQDPVSLKSSLSPRDENPCFIYLNCGPNGGEEILSVGVLSSARNMEVYLGEEYCGTSRGKTACTVLDDSEHEKILLYKKYLKLDSPTHACKIKLLSFGEKQCVLVSKVVVHLRPRSADPSPRSAALGSRIDLDNIQTIMESMGSRLSPGAQQLMSMIRFQQQNRLPIGDQLQSVLGSAGHKHLMALQSSPSPAVLDKASSTPFPFRTGLTPSAITENLKALIDKSAQPSGEGNTTNHDEGHLMPQNHSLESDLKNAVSSFLPKKASGSSSVPSSELLPFLQNLCSQVNHLRVGHNARWQENISKPREGMVGVPMEEQPVCSYLEKILSKNMELMEKKLMDHIDERIYQLQEHIDAKMALLVDLLRGPNSPPPGMPLRHYDSRERLSNGER","sequence_length":444,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"2c78201b5e01aa95608e1a3f5553d3963aee050bf60201af5edf276edf6a670a","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q9D2Q3.json","taxon_id":"10090","uniprot_accession":"Q9D2Q3","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/paat-like-pf14958.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF14958","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/paat-like-pf14958.yaml"}],"pfam_ids":["PF14958"],"protein_name":"ATPase PAAT","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"METRTEDGGLTRRPTLASSWDVAGGALTHSLLLTRAGLGPGDFDWEELLAPPAPGQDLVILKRNHNNKDENPCFLYLRCGPDGGEEIASIGILSSARNMEVYLGEEYCGTSRGKNVCTVLDDSEHEKIILYKKNLKLESSTHACKIKLLSFGERQCVFISKVVVHMRSVFANSSTSSPALGSRIDLDKVQTIMESMGSKLSPGAQQLMDMVRCQQRNCIPIGEQLQSVLGNSGYKHMIGLQSSSTLGTLNKSSSTPFPFRTGLTSGNVTENLQTYIDKSTQLPGGENSTKLDECKVMPQNHSFLENDLKNAMASFLPKKVSDNSNIPNSELLPFLQNLCSQVNHLHVGNKTECQENITKHGERILGVGMEEQSICSYLEKILSKNMELMEKKLMDYIDQRIHELQEHIDDKIALLLDLLQNPNSPPTGIPLRHYDSGERLSNGER","sequence_length":445,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"032e442444266a4f2d72c547449833f10150f2a3d1b196ea69ff7b775a7dfdbc","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q9H8K7.json","taxon_id":"9606","uniprot_accession":"Q9H8K7","uniprot_release":"2026_03"}],"pfam_id":"PF14958","short_name":"PAAT-like","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}