{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF14975","protein_label":"UPF0729 protein C18orf32 homolog","reviewed":true,"short_name":"DUF4512","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf4512-pf14975.yaml","source_record_id":"Pfam:PF14975","source_record_label":"Domain of unknown function (DUF4512)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10116","taxon_label":"Rattus norvegicus","uniprot_accession":"B1WC88","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF14975","protein_label":"UPF0729 protein C18orf32","reviewed":true,"short_name":"DUF4512","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf4512-pf14975.yaml","source_record_id":"Pfam:PF14975","source_record_label":"Domain of unknown function (DUF4512)","source_section":"canonical_examples","taxon_id":"NCBITaxon:9606","taxon_label":"Homo sapiens","uniprot_accession":"Q8TCD1","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF14975","protein_label":"UPF0729 protein C18orf32 homolog","reviewed":true,"short_name":"DUF4512","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf4512-pf14975.yaml","source_record_id":"Pfam:PF14975","source_record_label":"Domain of unknown function (DUF4512)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10090","taxon_label":"Mus musculus","uniprot_accession":"Q91WE4","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF14975","protein_label":"","reviewed":null,"short_name":"DUF4512","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf4512-pf14975.yaml","source_record_id":"Pfam:PF14975","source_record_label":"Domain of unknown function (DUF4512)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":1015,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":3,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family of proteins is found in eukaryotes. Proteins in this family are typically between 74 and 104 amino acids in length. There are two completely conserved residues (C and P) that may be functionally important.","domain_architectures":17,"interpro_id":"IPR026776","known_evidence_count":null,"matches":1125,"name":"Domain of unknown function (DUF4512)","partial_evidence_count":null,"pfam_id":"PF14975","proteins":1124,"proteomes":900,"short_name":"DUF4512","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14975","structures":0,"taxa":3064,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF14975.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":1015,"domain_architectures":17,"matches":1125,"proteins":1124,"proteomes":900,"structures":0,"taxa":3064},"curation_status":"SEEDED","description":"This family of proteins is found in eukaryotes. Proteins in this family are typically between 74 and 104 amino acids in length. There are two completely conserved residues (C and P) that may be functionally important.","id":"Pfam:PF14975","interpro_id":"InterPro:IPR026776","name":"Domain of unknown function (DUF4512)","pfam_id":"PF14975","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF4512","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF14975"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF14975.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"b03782b138c531f2b6b67f129bf14ef676e058d01b65df39b1461a976e751540"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Rattus norvegicus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf4512-pf14975.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF14975","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf4512-pf14975.yaml"}],"pfam_ids":["PF14975"],"protein_name":"UPF0729 protein C18orf32 homolog","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MVCIPCIVIPVLLWIFKKFLEPYIYPVVSRIWPRKAVQQLDNKNTGKVDCKGADTNGFSTKGPTEVSDKKKD","sequence_length":72,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"f88af0daa0fef8bd6d37201b08cd872b3e2896d6599046001150ca04dcdd55ce","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/B1WC88.json","taxon_id":"10116","uniprot_accession":"B1WC88","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf4512-pf14975.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF14975","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf4512-pf14975.yaml"}],"pfam_ids":["PF14975"],"protein_name":"UPF0729 protein C18orf32","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MVCIPCIVIPVLLWIYKKFLEPYIYPLVSPFVSRIWPKKAIQESNDTNKGKVNFKGADMNGLPTKGPTEICDKKKD","sequence_length":76,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"7531a9df52c07a1dc1840c7bb8fb3aa156f4dc09122393b7bee15edc2b7667bd","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q8TCD1.json","taxon_id":"9606","uniprot_accession":"Q8TCD1","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf4512-pf14975.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF14975","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf4512-pf14975.yaml"}],"pfam_ids":["PF14975"],"protein_name":"UPF0729 protein C18orf32 homolog","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MVCIPCIVIPVLLWIFKKFLEPYIYPVVSRIWPKKAVQQSGDKNMSKVDCKGAGTNGLPTKGPTEVSDKKKD","sequence_length":72,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"cb69b99f9b201ce7fc6ac574b7387b87edbae8b3480a075838f291df69b93efb","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q91WE4.json","taxon_id":"10090","uniprot_accession":"Q91WE4","uniprot_release":"2026_03"}],"pfam_id":"PF14975","short_name":"DUF4512","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}