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It may attenuate p53/TP53 activation through the E3 ubiquitin ligase HUWE1 which also promotes TAPR1's degradation [[cite:PUB00100199],[cite:PUB00101217]]. This family also includes uncharacterised proteins from fungi, such as YJR056C from yeast.","id":"Pfam:PF15251","interpro_id":"InterPro:IPR029196","name":"Telomere attrition and p53 response 1 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