{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF15429","protein_label":"Uncharacterized protein C1orf226","reviewed":true,"short_name":"DUF4628","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf4628-pf15429.yaml","source_record_id":"Pfam:PF15429","source_record_label":"Domain of unknown function (DUF4628)","source_section":"canonical_examples","taxon_id":"NCBITaxon:9606","taxon_label":"Homo sapiens","uniprot_accession":"A1L170","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF15429","protein_label":"Uncharacterized protein C1orf226 homolog","reviewed":true,"short_name":"DUF4628","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf4628-pf15429.yaml","source_record_id":"Pfam:PF15429","source_record_label":"Domain of unknown function (DUF4628)","source_section":"canonical_examples","taxon_id":"NCBITaxon:9913","taxon_label":"Bos taurus","uniprot_accession":"A4IFJ0","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF15429","protein_label":"","reviewed":null,"short_name":"DUF4628","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf4628-pf15429.yaml","source_record_id":"Pfam:PF15429","source_record_label":"Domain of unknown function (DUF4628)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":697,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family of proteins is found in eukaryotes. Proteins in this family are typically between 152 and 673 amino acids in length.","domain_architectures":8,"interpro_id":"IPR027851","known_evidence_count":null,"matches":872,"name":"Domain of unknown function (DUF4628)","partial_evidence_count":null,"pfam_id":"PF15429","proteins":853,"proteomes":502,"short_name":"DUF4628","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF15429","structures":0,"taxa":1657,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF15429.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":697,"domain_architectures":8,"matches":872,"proteins":853,"proteomes":502,"structures":0,"taxa":1657},"curation_status":"SEEDED","description":"This family of proteins is found in eukaryotes. Proteins in this family are typically between 152 and 673 amino acids in length.","id":"Pfam:PF15429","interpro_id":"InterPro:IPR027851","name":"Domain of unknown function (DUF4628)","pfam_id":"PF15429","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF4628","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF15429"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF15429.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"1f719e263498b1f3bc7beb9cf7b8decb39a1f693f80143ef53d0f32e67e28fc4"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf4628-pf15429.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF15429","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf4628-pf15429.yaml"}],"pfam_ids":["PF15429"],"protein_name":"Uncharacterized protein C1orf226","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MFENLNTALTPKLQASRSFPHLSKPVAPGSAPLGSGEPGGPGLWVGSSQHLKNLGKAMGAKVNDFLRRKEPSSLGSVGVTEINKTAGAQLASGTDAAPEAWLEDERSVLQETFPRLDPPPPITRKRTPRALKTTQDMLISSQPVLSSLEYGTEPSPGQAQDSAPTAQPDVPADASQPEATMEREERGKVLPNGEVSLSVPDLIHKDSQDESKLKMTECRRASSPSLIERNGFKLSLSPISLAESWEDGSPPPQARTSSLDNEGPHPDLLSFE","sequence_length":272,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"04b495482e347b99abd551e14ed0e375d6f9cf5197ec405db487e4cb5405fed1","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A1L170.json","taxon_id":"9606","uniprot_accession":"A1L170","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bos taurus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf4628-pf15429.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF15429","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf4628-pf15429.yaml"}],"pfam_ids":["PF15429"],"protein_name":"Uncharacterized protein C1orf226 homolog","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MFENLNTALTPKLQSSRSFPHLSRPTAPSAAAQGSVEPGGPGLWVGSSQHLKSLGKAVGAKVNDFLRRKEPSSLGSVGTTEVNKTAGAQLAGGADGDDGRSALQEAFPRLDPPPPATRKRTPRALKTTQDMLISSQPVLSSLEYGTELSSGQPQVSSSAQPSPADASQPEATTEVVDRDDALPNGEVSVSVPDLIHKDGQDDPKLKVTECRRASSPGLMERNGLKLSLSPISLAESPEDGSPPPRARTSSVDNEGPHPDLLSFE","sequence_length":264,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"90f82a2898cb976c7bf2c3ae0245ae2679400bda4a11e01d0ad24beb98b0a19c","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A4IFJ0.json","taxon_id":"9913","uniprot_accession":"A4IFJ0","uniprot_release":"2026_03"}],"pfam_id":"PF15429","short_name":"DUF4628","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}