{"cross_mech":[],"family":{"alphafold_models":148,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"LLCFC1 (also known as SOF1) and its homologues can be found in eukaryotes. They have two conserved sequence motifs: LLLL and CFNLAS. LLCFC1 is a sperm protein required for sperm-oocyte fusion in mice [[cite:PUB00094436]].","domain_architectures":2,"interpro_id":"IPR031684","known_evidence_count":null,"matches":176,"name":"LLLL and CFNLAS motif-containing protein 1","partial_evidence_count":null,"pfam_id":"PF15838","proteins":174,"proteomes":158,"short_name":"LLCFC1","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF15838","structures":0,"taxa":553,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF15838.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":148,"domain_architectures":2,"matches":176,"proteins":174,"proteomes":158,"structures":0,"taxa":553},"curation_status":"SEEDED","description":"LLCFC1 (also known as SOF1) and its homologues can be found in eukaryotes. They have two conserved sequence motifs: LLLL and CFNLAS. LLCFC1 is a sperm protein required for sperm-oocyte fusion in mice [[cite:PUB00094436]].","id":"Pfam:PF15838","interpro_id":"InterPro:IPR031684","name":"LLLL and CFNLAS motif-containing protein 1","pfam_id":"PF15838","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"LLCFC1","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF15838"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF15838.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"fdcdd8ba5802ddde50c72809c8f60bff02cc0697b573d2a28bc8b511a7df0509"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Homo sapiens","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/llcfc1-pf15838.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF15838","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/llcfc1-pf15838.yaml"}],"pfam_ids":["PF15838"],"protein_name":"Sperm-oocyte fusion protein 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MPPLAPQLCRAVFLVPILLLLQVKPLNGSPGPKDGSQTEKTPSADQNQEQFEEHFVASSVGEMWQVVDMAQQEEDQSSKTAAVHKHSFHLSFCFSLASVMVFSGGPLRRTFPNIQLCFMLTH","sequence_length":122,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"2e86a634467c4834b479f4eb8599f95456b6a7b20f116b0ba86975cc98a45100","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q96L11.json","taxon_id":"9606","uniprot_accession":"Q96L11","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mus musculus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/llcfc1-pf15838.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF15838","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/llcfc1-pf15838.yaml"}],"pfam_ids":["PF15838"],"protein_name":"Sperm-oocyte fusion protein 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MTSLGSQLHRATFLTALLLLLLLQVKGVKTLIVSASLDGDKSQKDKVSSEDQGEEEYEEHFEASSEGEQWQEIDMVQQEDTISQAITLQDHLLDLAFCFNLASIMFFL","sequence_length":108,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"e0a26c50728a06ddbf2f23207e6130ec3e38f14578bf7cc51e617fec33159d3d","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/Q9D9P8.json","taxon_id":"10090","uniprot_accession":"Q9D9P8","uniprot_release":"2026_03"}],"pfam_id":"PF15838","short_name":"LLCFC1","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}