{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF16086","protein_label":"","reviewed":null,"short_name":"DUF4816","source_category":"sequence/repeat/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/repeat/pfam/duf4816-pf16086.yaml","source_record_id":"Pfam:PF16086","source_record_label":"Domain of unknown function (DUF4816)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":498,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family of proteins is functionally uncharacterised. This family of proteins is found in insects. This region contains a repeat rich in tryptophan and lysine. Structure prediction suggests that these repeats for extended helical twisting pairs of antiparallel beta strands.","domain_architectures":20,"interpro_id":"IPR032134","known_evidence_count":null,"matches":2022,"name":"Domain of unknown function (DUF4816)","partial_evidence_count":null,"pfam_id":"PF16086","proteins":579,"proteomes":235,"short_name":"DUF4816","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16086","structures":0,"taxa":842,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF16086.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":498,"domain_architectures":20,"matches":2022,"proteins":579,"proteomes":235,"structures":0,"taxa":842},"curation_status":"SEEDED","description":"This family of proteins is functionally uncharacterised. This family of proteins is found in insects. This region contains a repeat rich in tryptophan and lysine. Structure prediction suggests that these repeats for extended helical twisting pairs of antiparallel beta strands.","id":"Pfam:PF16086","interpro_id":"InterPro:IPR032134","name":"Domain of unknown function (DUF4816)","pfam_id":"PF16086","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF4816","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16086"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF16086.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"9f8d6dcd8d027ee4181196f50ca2fcbfba4e6c9e9ebf12b5915f016f3a1819ce"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF16086","short_name":"DUF4816","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}