{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF16161","protein_label":"","reviewed":null,"short_name":"DUF4867","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf4867-pf16161.yaml","source_record_id":"Pfam:PF16161","source_record_label":"Domain of unknown function (DUF4867)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":306,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family consists of uncharacterised proteins around 220 residues in length and is mainly found in various human gut Firmicutes and a few eubacteria species. It is also amply represented in human gut metagenomic datasets. Distant homology analysis and marginal HMM overlaps suggest this family is a distant homologue of Ureidoglycolate hydrolase [pfam:PF04115], but this prediction is not verified by experiment, therefore the function of this family is still unknown.","domain_architectures":2,"interpro_id":"IPR032358","known_evidence_count":null,"matches":452,"name":"Domain of unknown function (DUF4867)","partial_evidence_count":null,"pfam_id":"PF16161","proteins":452,"proteomes":424,"short_name":"DUF4867","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16161","structures":2,"taxa":771,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF16161.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":306,"domain_architectures":2,"matches":452,"proteins":452,"proteomes":424,"structures":2,"taxa":771},"curation_status":"SEEDED","description":"This family consists of uncharacterised proteins around 220 residues in length and is mainly found in various human gut Firmicutes and a few eubacteria species. It is also amply represented in human gut metagenomic datasets. Distant homology analysis and marginal HMM overlaps suggest this family is a distant homologue of Ureidoglycolate hydrolase [pfam:PF04115], but this prediction is not verified by experiment, therefore the function of this family is still unknown.","id":"Pfam:PF16161","interpro_id":"InterPro:IPR032358","name":"Domain of unknown function (DUF4867)","pfam_id":"PF16161","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF4867","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16161"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF16161.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"36cf9af921795c058534f568f1a01973bd0b831b911f74cd7c08f3c7a6d48bd7"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF16161","short_name":"DUF4867","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}