{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF16244","protein_label":"Uncharacterized protein YcdB","reviewed":true,"short_name":"DUF4901","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/ycdb-ycdc-repeated-domain-ipr032599.yaml","source_record_id":"InterPro:IPR032599","source_record_label":"YcdB/YcdC, repeated domain","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"O34621","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF16244","protein_label":"Uncharacterized protein YcdC","reviewed":true,"short_name":"DUF4901","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/ycdb-ycdc-repeated-domain-ipr032599.yaml","source_record_id":"InterPro:IPR032599","source_record_label":"YcdB/YcdC, repeated domain","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"O34772","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF16244","protein_label":"","reviewed":null,"short_name":"DUF4901","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/ycdb-ycdc-repeated-domain-ipr032599.yaml","source_record_id":"InterPro:IPR032599","source_record_label":"YcdB/YcdC, repeated domain","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF16244","protein_label":"Uncharacterized protein YcdB","reviewed":true,"short_name":"DUF4901","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf4901-pf16244.yaml","source_record_id":"Pfam:PF16244","source_record_label":"YcdB, YcdC repeated domain","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"O34621","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF16244","protein_label":"Uncharacterized protein YcdC","reviewed":true,"short_name":"DUF4901","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf4901-pf16244.yaml","source_record_id":"Pfam:PF16244","source_record_label":"YcdB, YcdC repeated domain","source_section":"canonical_examples","taxon_id":"NCBITaxon:224308","taxon_label":"Bacillus subtilis (strain 168)","uniprot_accession":"O34772","unknown_status":"KNOWN_HISTORICAL_DUF"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF16244","protein_label":"","reviewed":null,"short_name":"DUF4901","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf4901-pf16244.yaml","source_record_id":"Pfam:PF16244","source_record_label":"YcdB, YcdC repeated domain","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"KNOWN_HISTORICAL_DUF"}],"family":{"alphafold_models":805,"candidate_reasons":["short_name_matches_duf"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":2},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents a domain that is generally found in two copies in YcdB and YcdC from B. subtilis. These proteins are uncharacterised. The C-terminal half of this domain appears to show similarity at the sequence level to the PEPSY domain.","domain_architectures":22,"interpro_id":"IPR032599","known_evidence_count":null,"matches":2002,"name":"YcdB, YcdC repeated domain","partial_evidence_count":null,"pfam_id":"PF16244","proteins":1211,"proteomes":732,"short_name":"DUF4901","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16244","structures":0,"taxa":1130,"unknown_status":"KNOWN_HISTORICAL_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF16244.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":805,"domain_architectures":22,"matches":2002,"proteins":1211,"proteomes":732,"structures":0,"taxa":1130},"curation_status":"SEEDED","description":"This entry represents a domain that is generally found in two copies in YcdB and YcdC from B. subtilis. These proteins are uncharacterised. The C-terminal half of this domain appears to show similarity at the sequence level to the PEPSY domain.","id":"Pfam:PF16244","interpro_id":"InterPro:IPR032599","name":"YcdB, YcdC repeated domain","pfam_id":"PF16244","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"KNOWN_HISTORICAL_DUF","short_name":"DUF4901","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16244"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF16244.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"5e057736d46ab8d3c5ceb70170919a839dc760dca2bde39794c6842212cde280"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacillus subtilis (strain 168)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/ycdb-ycdc-repeated-domain-ipr032599.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR032599","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/ycdb-ycdc-repeated-domain-ipr032599.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf4901-pf16244.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF16244","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf4901-pf16244.yaml"}],"pfam_ids":["PF16244"],"protein_name":"Uncharacterized protein YcdB","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MKGAAFVKKEGLKQKALEIGRVPTHLKLEIEDYGGDDKRAHFCWADPQDENTGIIVELGPDGELESLSRDIEPESGERLSEEKLEDIMRQFVETHHPGALSAFVREENDRAYGDKVRFSYVQMEAGLPLPMSGFMADVSLSGEIVYFRYYGEAGSIIKPKRVADVEEALAFIKKDVEFDLLFEVLHRSVYKNGDDQPHLVYEPEGRAITVPADLVQEEQAVDDDDDYREPESFPLPLFEGIREKADPDSMIGIENGFVKEREADLGDGRIGIVWRNPDDPVYQPADKSMDSWFKGRTHQVLKTIYNKETGKLEGVMSFMEKKGPLTVTLAECEKIALRFLFALFPNADQYFRIRYDEKDEEENAVAGFTFEAHCHGVPLRFGQIRICVSRQTGYITVYMGPDIDPNKLATIDPVPAISVEQAKSIFWQHFKVELGWEREYGDDEEHSYRLVYKPVYPHFIDAHTGEPVFSIW","sequence_length":472,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"1829771da092527849fcf22b13824261d1896b7ec5c8eb28c5ac0cc93737206c","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/O34621.json","taxon_id":"224308","uniprot_accession":"O34621","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacillus subtilis (strain 168)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/ycdb-ycdc-repeated-domain-ipr032599.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR032599","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/ycdb-ycdc-repeated-domain-ipr032599.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf4901-pf16244.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF16244","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf4901-pf16244.yaml"}],"pfam_ids":["PF16244"],"protein_name":"Uncharacterized protein YcdC","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MVNKQLKKKAQEIGNVPTHYELEIEDYDQKQKKYGQAYFIWKDPKDPEKHITVELRNDGALLTFSTTVHSETDKKLPDAELKLTALQFAAANHPGTFMNFHFQGKEERGQHIRFVYTKMELGLPIPNSGFLIDMTRSGQIVHFLYYGEGHKAEVPTEFVAKEKVVSHYLNTMSFELMYDVIDGEQEPRLVYEPILPGYSYPADVDEIVPDQHIADERIENTAPLPPLQNKEEVDIFALLGFTSDMQKVSERDFGEQIGSTWRRGAAPERKDLSIGSYFETRNKNTIKMKTDKRTGKLKAALSFMDWRNNLQCSTEECQEIALQFLYALYPRAAEFFRVNPVRIDERGRVRNHFSVWYKGVPLRFGAARIIVNPETGLIDAFMAPDIEPEQLEAINHRPDVSAEEAKEAFLAAFDVKLEWQPDFTAGSDQHCKLVYKPVYPSYIDAHIRKKKRL","sequence_length":453,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"2e5b9935b81a6c11cdd1f0e268e8e888003b132899e2b3500dceb7e4e10a020c","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/O34772.json","taxon_id":"224308","uniprot_accession":"O34772","uniprot_release":"2026_03"}],"pfam_id":"PF16244","short_name":"DUF4901","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}