{"cross_mech":[],"family":{"alphafold_models":345,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"SusE and SusF are two outer membrane proteins composed of tandem starch specific carbohydrate binding modules (CBMs) with no enzymatic activity. They are are likely to play an important role in starch metabolism in Bacteroides. It has been speculated that they could compete for starch in the human intestinal tract by sequestering starch at the bacterial surface and away from competitors [[cite:PUB00062486]]. SusE has higher affinity for starch compared to SusF. SusE contains two starch specific CBMs whereas SusF contains three. This entry represents the two SusE and the second and third SusF CBMs.","domain_architectures":26,"interpro_id":"IPR032187","known_evidence_count":null,"matches":670,"name":"SusF/SusE starch specific CBMs","partial_evidence_count":null,"pfam_id":"PF16411","proteins":498,"proteomes":442,"short_name":"SusF_SusE","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16411","structures":3,"taxa":686,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF16411.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":345,"domain_architectures":26,"matches":670,"proteins":498,"proteomes":442,"structures":3,"taxa":686},"curation_status":"SEEDED","description":"SusE and SusF are two outer membrane proteins composed of tandem starch specific carbohydrate binding modules (CBMs) with no enzymatic activity. They are are likely to play an important role in starch metabolism in Bacteroides. It has been speculated that they could compete for starch in the human intestinal tract by sequestering starch at the bacterial surface and away from competitors [[cite:PUB00062486]]. SusE has higher affinity for starch compared to SusF. SusE contains two starch specific CBMs whereas SusF contains three. This entry represents the two SusE and the second and third SusF CBMs.","id":"Pfam:PF16411","interpro_id":"InterPro:IPR032187","name":"SusF/SusE starch specific CBMs","pfam_id":"PF16411","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"SusF_SusE","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF16411"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF16411.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"66ce530b3df96831935e7c75052cdfc30dd43b10826a056c0bec45ae6812706e"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/cbm-1st-susf-pf26120.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF26120","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/cbm-1st-susf-pf26120.yaml"}],"pfam_ids":["PF16411","PF17142","PF26120"],"protein_name":"Outer membrane protein SusF","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MKKHLIYTGMFLAAIGFSACNEDFKDWADPQSNPQEESAGQLTATFTAGKDASIVMDAATADSVEIAKLSSTTAEEGSKIAVNSLTLNENHTIPFSMTEDHVFKVALAQLDSVTQEAYKSRASVVRELKISINASAVTPSGEGIQLVGNEVSITLQPATTPAVDPDGYYIVGDFTGWDGNSAQQMKKDALDENLYILEAEIESTSNFKIFPASAINGNDIDWTKALGSSVDGDDSGDNFVSWTNAGAINTALDGKIKISFDAFNYRFTVKDNSAPTELYMTGSAYNWGTPAGDPNAWKALVPVNGTKGTFWGIFYFAANDQVKFAPQANWGNDFGFVDAISQESKDLAGLSDEGGNLKVGIAGWYLVYVSVIGDDKVIEFEKPNVYLMGDTSYNGWDAQLVEQDLFTVPGTADGEFVSPAFLKDGAVRICVNPKAVSAGDWWKTEFIIFDGQIAYRGNGGDQAAVQGKTGQKVYLNFGNGTGRIE","sequence_length":485,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"62e4f09ed5ecac5c29419188e0dec044aa7396fdcf77a07f8fbabc256685b735","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/G8JZS6.json","taxon_id":"226186","uniprot_accession":"G8JZS6","uniprot_release":"2026_03"}],"pfam_id":"PF16411","short_name":"SusF_SusE","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}