{"cross_mech":[],"family":{"alphafold_models":65,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain is N-terminal in outer membrane protein SusF from Bacteroides thetaiotaomicron and similar sequences from bacteroidetes. SusF is a starch-binding protein organised into three tandem domains packed against each other: N-terminal (this entry), middle, and C-terminal. The last two, represented by [pfam:PF16411], are common to SusE and SusF. This domain forms a beta-sandwich that is similar in overall-fold and topology to several immunoglobulin superfamily domains found in cell adhesion proteins [[cite:PUB00062486]].","domain_architectures":10,"interpro_id":"IPR033408","known_evidence_count":null,"matches":85,"name":"Outer membrane protein SusF, N-terminal domain","partial_evidence_count":null,"pfam_id":"PF17142","proteins":84,"proteomes":83,"short_name":"SusF_N","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17142","structures":1,"taxa":147,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF17142.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":65,"domain_architectures":10,"matches":85,"proteins":84,"proteomes":83,"structures":1,"taxa":147},"curation_status":"SEEDED","description":"This domain is N-terminal in outer membrane protein SusF from Bacteroides thetaiotaomicron and similar sequences from bacteroidetes. SusF is a starch-binding protein organised into three tandem domains packed against each other: N-terminal (this entry), middle, and C-terminal. The last two, represented by [pfam:PF16411], are common to SusE and SusF. This domain forms a beta-sandwich that is similar in overall-fold and topology to several immunoglobulin superfamily domains found in cell adhesion proteins [[cite:PUB00062486]].","id":"Pfam:PF17142","interpro_id":"InterPro:IPR033408","name":"Outer membrane protein SusF, N-terminal domain","pfam_id":"PF17142","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"SusF_N","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17142"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF17142.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"e75179221617dbd76d829febc277af5e6a280d58932bc28e04bcf3ddaadb0340"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/cbm-1st-susf-pf26120.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF26120","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/cbm-1st-susf-pf26120.yaml"}],"pfam_ids":["PF16411","PF17142","PF26120"],"protein_name":"Outer membrane protein SusF","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MKKHLIYTGMFLAAIGFSACNEDFKDWADPQSNPQEESAGQLTATFTAGKDASIVMDAATADSVEIAKLSSTTAEEGSKIAVNSLTLNENHTIPFSMTEDHVFKVALAQLDSVTQEAYKSRASVVRELKISINASAVTPSGEGIQLVGNEVSITLQPATTPAVDPDGYYIVGDFTGWDGNSAQQMKKDALDENLYILEAEIESTSNFKIFPASAINGNDIDWTKALGSSVDGDDSGDNFVSWTNAGAINTALDGKIKISFDAFNYRFTVKDNSAPTELYMTGSAYNWGTPAGDPNAWKALVPVNGTKGTFWGIFYFAANDQVKFAPQANWGNDFGFVDAISQESKDLAGLSDEGGNLKVGIAGWYLVYVSVIGDDKVIEFEKPNVYLMGDTSYNGWDAQLVEQDLFTVPGTADGEFVSPAFLKDGAVRICVNPKAVSAGDWWKTEFIIFDGQIAYRGNGGDQAAVQGKTGQKVYLNFGNGTGRIE","sequence_length":485,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"62e4f09ed5ecac5c29419188e0dec044aa7396fdcf77a07f8fbabc256685b735","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/G8JZS6.json","taxon_id":"226186","uniprot_accession":"G8JZS6","uniprot_release":"2026_03"}],"pfam_id":"PF17142","short_name":"SusF_N","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}