{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF17174","protein_label":"Uncharacterized protein MSMEG_4692/MSMEI_4575","reviewed":true,"short_name":"DUF5130","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf5130-pf17174.yaml","source_record_id":"Pfam:PF17174","source_record_label":"Domain of unknown function (DUF5130)","source_section":"canonical_examples","taxon_id":"NCBITaxon:246196","taxon_label":"Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)","uniprot_accession":"A0R1B5","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF17174","protein_label":"Uncharacterized protein MT2543","reviewed":true,"short_name":"DUF5130","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf5130-pf17174.yaml","source_record_id":"Pfam:PF17174","source_record_label":"Domain of unknown function (DUF5130)","source_section":"canonical_examples","taxon_id":"NCBITaxon:83331","taxon_label":"Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)","uniprot_accession":"P9WLA6","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF17174","protein_label":"Uncharacterized protein Rv2468c","reviewed":true,"short_name":"DUF5130","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf5130-pf17174.yaml","source_record_id":"Pfam:PF17174","source_record_label":"Domain of unknown function (DUF5130)","source_section":"canonical_examples","taxon_id":"NCBITaxon:83332","taxon_label":"Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)","uniprot_accession":"P9WLA7","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF17174","protein_label":"","reviewed":null,"short_name":"DUF5130","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf5130-pf17174.yaml","source_record_id":"Pfam:PF17174","source_record_label":"Domain of unknown function (DUF5130)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":871,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":3,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"","domain_architectures":1,"interpro_id":"IPR033437","known_evidence_count":null,"matches":1365,"name":"Domain of unknown function (DUF5130)","partial_evidence_count":null,"pfam_id":"PF17174","proteins":1365,"proteomes":1359,"short_name":"DUF5130","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17174","structures":16,"taxa":1633,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF17174.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":871,"domain_architectures":1,"matches":1365,"proteins":1365,"proteomes":1359,"structures":16,"taxa":1633},"curation_status":"SEEDED","id":"Pfam:PF17174","interpro_id":"InterPro:IPR033437","name":"Domain of unknown function (DUF5130)","pfam_id":"PF17174","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF5130","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17174"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF17174.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"010d4ec7bf2ff593d8b3b0e756ad72682f9537885815cf95f961c1910abda4d4"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf5130-pf17174.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF17174","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf5130-pf17174.yaml"}],"pfam_ids":["PF17174"],"protein_name":"Uncharacterized protein MSMEG_4692/MSMEI_4575","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MASGDIATVANAELDLPYGSALTSSGRISAVTEPGELSVHYPFPTMDLVVLDDALKYGSRAAKARFAVYIGPLGADTAATAREILANVPTPENAVLLAVSPDQRAIEVVYGADVKGRGIESAAPLGVSAAAASFKEGNLIDGLISAVRVMSAGVSPA","sequence_length":157,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"536bdbbb98757b5983c7f67a325baf5aee1773ee5d780d0b62aeebe8744d0c7f","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A0R1B5.json","taxon_id":"246196","uniprot_accession":"A0R1B5","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf5130-pf17174.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF17174","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf5130-pf17174.yaml"}],"pfam_ids":["PF17174"],"protein_name":"Uncharacterized protein MT2543","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MTHRSSRLEVGPVARGDVATIEHAELPPGWVLTTSGRISGVTEPGELSVHYPFPIADLVALDDALTYSSRACQVRFAIYLGDLGRDTAARAREILGKVPTPDNAVLLAVSPNQCAIEVVYGSQVRGRGAESAAPLGVAAASSAFEQGELVDGLISAIRVLSAGIAPG","sequence_length":167,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"a0f28d8e6c76724d4d793af38008b999297d029fccfa922132a34a6589157240","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P9WLA6.json","taxon_id":"83331","uniprot_accession":"P9WLA6","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf5130-pf17174.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF17174","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf5130-pf17174.yaml"}],"pfam_ids":["PF17174"],"protein_name":"Uncharacterized protein Rv2468c","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MTHRSSRLEVGPVARGDVATIEHAELPPGWVLTTSGRISGVTEPGELSVHYPFPIADLVALDDALTYSSRACQVRFAIYLGDLGRDTAARAREILGKVPTPDNAVLLAVSPNQCAIEVVYGSQVRGRGAESAAPLGVAAASSAFEQGELVDGLISAIRVLSAGIAPG","sequence_length":167,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"a0f28d8e6c76724d4d793af38008b999297d029fccfa922132a34a6589157240","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P9WLA7.json","taxon_id":"83332","uniprot_accession":"P9WLA7","uniprot_release":"2026_03"}],"pfam_id":"PF17174","short_name":"DUF5130","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}