{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF17258","protein_label":"Putative nosiheptide resistance regulatory protein","reviewed":true,"short_name":"DUF5324","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf5324-pf17258.yaml","source_record_id":"Pfam:PF17258","source_record_label":"Family of unknown function (DUF5324)","source_section":"canonical_examples","taxon_id":"NCBITaxon:1885","taxon_label":"Streptomyces actuosus","uniprot_accession":"P52392","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF17258","protein_label":"","reviewed":null,"short_name":"DUF5324","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf5324-pf17258.yaml","source_record_id":"Pfam:PF17258","source_record_label":"Family of unknown function (DUF5324)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":368,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":1,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This is a family of unknown function, mostly found in Actinobacteria. Most of the family members contain one trans-membrane domain.","domain_architectures":2,"interpro_id":"IPR035214","known_evidence_count":null,"matches":850,"name":"Family of unknown function (DUF5324)","partial_evidence_count":null,"pfam_id":"PF17258","proteins":850,"proteomes":841,"short_name":"DUF5324","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17258","structures":0,"taxa":919,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF17258.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":368,"domain_architectures":2,"matches":850,"proteins":850,"proteomes":841,"structures":0,"taxa":919},"curation_status":"SEEDED","description":"This is a family of unknown function, mostly found in Actinobacteria. Most of the family members contain one trans-membrane domain.","id":"Pfam:PF17258","interpro_id":"InterPro:IPR035214","name":"Family of unknown function (DUF5324)","pfam_id":"PF17258","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF5324","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17258"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF17258.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"82f86299ae24fbcb4f360ec8dc01ee6472ffa6cdb2da44137b7f56fc5b3ab7ff"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Streptomyces actuosus","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf5324-pf17258.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF17258","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf5324-pf17258.yaml"}],"pfam_ids":["PF17258"],"protein_name":"Putative nosiheptide resistance regulatory protein","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MTRIDSVRAATGSAKDSVLHAAEVVAPYADTAKERAAHYAHEARVRLAPKVTLAAEQARVQYGAHLAPRLEQARTHVPPKVELAAQEAALRTRKAARQAADYSRPMIEQAVAAAGPVRDEAATRAAAALVALRGQVTAEDIQKLVRKHERRARTGRAVRMLAVLGLVAGGAFAAWKWWDKQANPDWLVEPPEATEVPESGRLTSVDGSAEAVLDPEVQAKEAAEEAAKRDDQA","sequence_length":233,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"5e2bd8bee94f2141b70a0d5abb540867c478ce7d33acd8c187705b409d25cef8","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P52392.json","taxon_id":"1885","uniprot_accession":"P52392","uniprot_release":"2026_03"}],"pfam_id":"PF17258","short_name":"DUF5324","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}