{"cross_mech":[],"family":{"alphafold_models":5143,"candidate_reasons":["description_says_unknown_function","pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents the NTF2-like domain found in the functionally uncharacterised YchJ family protein from Psychrobacter arcticus and related proteins. This domain is usually found flanked by either ([pfam:PF21612]) and ([pfam:PF02810]) at the N and C terminus or flanked on both sides by ([pfam:PF02810]]). The structure of YchJ shows that this domain adopts structure typical for Nuclear transport factor 2 (NTF2) that consists of a curved three-stranded beta-sheet and array of alpha-helices packed on one side of it. The function of this domain is unknown.","domain_architectures":24,"interpro_id":"IPR048469","known_evidence_count":null,"matches":8609,"name":"YchJ, middle NTF2-like domain","partial_evidence_count":null,"pfam_id":"PF17775","proteins":8600,"proteomes":8365,"short_name":"YchJ_M-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17775","structures":4,"taxa":11015,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF17775.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":5143,"domain_architectures":24,"matches":8609,"proteins":8600,"proteomes":8365,"structures":4,"taxa":11015},"curation_status":"SEEDED","description":"This entry represents the NTF2-like domain found in the functionally uncharacterised YchJ family protein from Psychrobacter arcticus and related proteins. This domain is usually found flanked by either ([pfam:PF21612]) and ([pfam:PF02810]) at the N and C terminus or flanked on both sides by ([pfam:PF02810]]). The structure of YchJ shows that this domain adopts structure typical for Nuclear transport factor 2 (NTF2) that consists of a curved three-stranded beta-sheet and array of alpha-helices packed on one side of it. The function of this domain is unknown.","id":"Pfam:PF17775","interpro_id":"InterPro:IPR048469","name":"YchJ, middle NTF2-like domain","pfam_id":"PF17775","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"YchJ_M-like","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17775"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF17775.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"374f048aed9cc689baa2b0dc777b20e259dd41f4051943bbb7f08b032c46e9f8"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/hypothetical-protein-nf002449.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF002449","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/hypothetical-protein-nf002449.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/ychj-family-protein-nf002486.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF002486","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/ychj-family-protein-nf002486.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/conservation/interpro/sec-c-motif-ipr004027.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR004027","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/conservation/interpro/sec-c-motif-ipr004027.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/ychj-like-middle-ntf2-like-domain-ipr048469.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR048469","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/ychj-like-middle-ntf2-like-domain-ipr048469.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/sec-c-pf02810.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF02810","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/sec-c-pf02810.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/ychj-m-like-pf17775.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF17775","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/ychj-m-like-pf17775.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P37052","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF02810","PF17775"],"protein_name":"UPF0225 protein YchJ","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"45c69a28e2c0f644959cb6819e2725237c240c4f2ccaf436bf6ad01b47fc2335","sequence_version":2,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQDADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTEGGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ","sequence_length":152,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"45c69a28e2c0f644959cb6819e2725237c240c4f2ccaf436bf6ad01b47fc2335","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/P37052.json","taxon_id":"83333","uniprot_accession":"P37052","uniprot_release":"2026_03"}],"pfam_id":"PF17775","short_name":"YchJ_M-like","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}