{"cross_mech":[],"family":{"alphafold_models":973,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain is found in the probable cell wall elongation regulator TseB from Bacillus subtilis and similar sequences from firmicutes. TseB is required for normal cell shape. It plays an important role in cell wall elongation during exponential phase and spore outgrowth [[cite:PUB00105892]]. This domain shows an alpha-beta structure.","domain_architectures":2,"interpro_id":"IPR041401","known_evidence_count":null,"matches":1545,"name":"Cell wall elongation regulator TseB-like domain","partial_evidence_count":null,"pfam_id":"PF17881","proteins":1545,"proteomes":1544,"short_name":"TseB","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17881","structures":1,"taxa":1991,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF17881.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":973,"domain_architectures":2,"matches":1545,"proteins":1545,"proteomes":1544,"structures":1,"taxa":1991},"curation_status":"SEEDED","description":"This domain is found in the probable cell wall elongation regulator TseB from Bacillus subtilis and similar sequences from firmicutes. TseB is required for normal cell shape. It plays an important role in cell wall elongation during exponential phase and spore outgrowth [[cite:PUB00105892]]. This domain shows an alpha-beta structure.","id":"Pfam:PF17881","interpro_id":"InterPro:IPR041401","name":"Cell wall elongation regulator TseB-like domain","pfam_id":"PF17881","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"TseB","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF17881"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF17881.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"61a46dad1cd013cd8743c072852d590889bcb25a61186eed056be67e0fb8069d"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacillus subtilis (strain 168)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/function/protein_family/ncbifam/cell-wall-elongation-penicillin-binding-protein-regulator-tseb-nf040668.yaml","qualification_status":"NOT_ASSESSED","record_id":"NCBIfam:NF040668","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/function/protein_family/ncbifam/cell-wall-elongation-penicillin-binding-protein-regulator-tseb-nf040668.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/cell-wall-elongation-regulator-tseb-like-domain-ipr041401.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR041401","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/cell-wall-elongation-regulator-tseb-like-domain-ipr041401.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/pepsy-domain-ipr025711.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR025711","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/pepsy-domain-ipr025711.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/pepsy-pf03413.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF03413","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/pepsy-pf03413.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/tseb-pf17881.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF17881","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/tseb-pf17881.yaml"}],"pfam_ids":["PF03413","PF17881"],"protein_name":"Probable cell wall elongation regulator TseB","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MRKKALIFTVIFGIIFLAVLLVSASIYKSAMAQKEEGHEAAAAEAKKETDLAHVDQVETFVGKEKYYVVKGTDKKGTALYVWVPADKKAKILSKEAKEGISEDKAAKIIKDEGLVSKQKEVHLAREGNVLLWEVTYLDKEGQYSLSYVDFTTGKILKNITP","sequence_length":161,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"4f5f395d11096a906ac88b0f8cca1e4f4d0c7e574b97a2b7181050d4e06db468","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P54396.json","taxon_id":"224308","uniprot_accession":"P54396","uniprot_release":"2026_03"}],"pfam_id":"PF17881","short_name":"TseB","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}