{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF19087","protein_label":"","reviewed":null,"short_name":"DUF5776","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf5776-ipr044081.yaml","source_record_id":"InterPro:IPR044081","source_record_label":"Domain of unknown function DUF5776","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF19087","protein_label":"Endolysin","reviewed":true,"short_name":"DUF5776","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf5776-pf19087.yaml","source_record_id":"Pfam:PF19087","source_record_label":"Domain of unknown function (DUF5776)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10724","taxon_label":"Bacillus phage SPP1","uniprot_accession":"O48471","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF19087","protein_label":"L-alanyl-D-glutamate peptidase","reviewed":true,"short_name":"DUF5776","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf5776-pf19087.yaml","source_record_id":"Pfam:PF19087","source_record_label":"Domain of unknown function (DUF5776)","source_section":"canonical_examples","taxon_id":"NCBITaxon:40521","taxon_label":"Listeria phage A118","uniprot_accession":"Q37976","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF19087","protein_label":"","reviewed":null,"short_name":"DUF5776","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf5776-pf19087.yaml","source_record_id":"Pfam:PF19087","source_record_label":"Domain of unknown function (DUF5776)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":588,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"Presumed stalk domain found in bacterial surface proteins forming tandem repeats with high sequence identity. This domain is also associated with other known bacterial surface protein stalks and adhesive domains.","domain_architectures":167,"interpro_id":"IPR044081","known_evidence_count":null,"matches":1620,"name":"Domain of unknown function (DUF5776)","partial_evidence_count":null,"pfam_id":"PF19087","proteins":1144,"proteomes":333,"short_name":"DUF5776","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF19087","structures":4,"taxa":537,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF19087.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":588,"domain_architectures":167,"matches":1620,"proteins":1144,"proteomes":333,"structures":4,"taxa":537},"curation_status":"SEEDED","description":"Presumed stalk domain found in bacterial surface proteins forming tandem repeats with high sequence identity. This domain is also associated with other known bacterial surface protein stalks and adhesive domains.","id":"Pfam:PF19087","interpro_id":"InterPro:IPR044081","name":"Domain of unknown function (DUF5776)","pfam_id":"PF19087","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF5776","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF19087"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF19087.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"b9f79d2ab6c1122086a9060cf0c73cd5f5f3a2bf2251036e98a1b530d16cfec1"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Bacillus phage SPP1","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf5776-pf19087.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF19087","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf5776-pf19087.yaml"}],"pfam_ids":["PF01520","PF19087"],"protein_name":"Endolysin","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSKLVWLDAGHGGKDSGAAANGIKEKDIVLKIVKKVKSILTSRYEVAVKLTRDSDVFYELIDRARKANAAKADLFVSVHINATPGGKGFETYRYVKTSASSSTGQQQKVLHDAIYKRIKKYGIKDRGEKAADLSVLRNTSMPAVLTENLFIDNKDEAALLKKDSFLNDVAEGHAEGIAEILNLKKKSGGSAPKKEDKPSSGKTKMVIVKDNPDGFLWVYNKADWNARYKKVKPDEAFTIDKTVTVNGSKMYKLKSGLYITAASKYVTVKEK","sequence_length":271,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"c2ad0fb92ca86f51bbace41c370d82a8fa2d12a1919e008c0a32c1ca62322fdc","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/O48471.json","taxon_id":"10724","uniprot_accession":"O48471","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Listeria phage A118","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf5776-pf19087.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF19087","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf5776-pf19087.yaml"}],"pfam_ids":["PF13539","PF19087"],"protein_name":"L-alanyl-D-glutamate peptidase","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MTSYYYSRSLANVNKLADNTKAAARKLLDWSESNGIEVLIYETIRTKEQQAANVNSGASQTMRSYHLVGQALDFVMAKGKTVDWGAYRSDKGKKFVAKAKSLGFEWGGDWSGFVDNPHLQFNYKGYGTDTFGKGASTSNSSKPSADTNTNSLGLVDYMNLNKLDSSFANRKKLATSYGIKNYSGTATQNTTLLAKLKAGKPHTPASKNTYYTENPRKVKTLVQCDLYKSVDFTTKNQTGGTFPPGTVFTISGMGKTKGGTPRLKTKSGYYLTANTKFVKKI","sequence_length":281,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"ac4001d39c4939de5891f04b1987c84c773d9f66982e2adf9704c32825899140","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q37976.json","taxon_id":"40521","uniprot_accession":"Q37976","uniprot_release":"2026_03"}],"pfam_id":"PF19087","short_name":"DUF5776","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}
