{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["uniprot_pfam_xref"],"pfam_id":"PF19156","protein_label":"MusF1","reviewed":false,"short_name":"DUF5838","source_category":"amino_acids_and_peptides","source_mech":"NaturalProductMech","source_path":"data/natural_products/amino_acids_and_peptides/muscoride-a.yaml","source_record_id":"naturalproductmech:mibig-3dbef7a0f0","source_record_label":"muscoride A","source_section":"uniprot_accession","taxon_id":"NCBITaxon:2665154","taxon_label":"Nostoc sp. UHCC-0398","uniprot_accession":"A0A5Q0TWZ6","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["uniprot_pfam_xref"],"pfam_id":"PF19156","protein_label":"MusF2","reviewed":false,"short_name":"DUF5838","source_category":"amino_acids_and_peptides","source_mech":"NaturalProductMech","source_path":"data/natural_products/amino_acids_and_peptides/muscoride-a.yaml","source_record_id":"naturalproductmech:mibig-3dbef7a0f0","source_record_label":"muscoride A","source_section":"uniprot_accession","taxon_id":"NCBITaxon:2665154","taxon_label":"Nostoc sp. UHCC-0398","uniprot_accession":"A0A5Q0TX00","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["uniprot_pfam_xref"],"pfam_id":"PF19156","protein_label":"MusF1","reviewed":false,"short_name":"DUF5838","source_category":"unclassified","source_mech":"NaturalProductMech","source_path":"data/natural_products/unclassified/muscoride-b.yaml","source_record_id":"naturalproductmech:mibig-f4bf230570","source_record_label":"muscoride B","source_section":"uniprot_accession","taxon_id":"NCBITaxon:2665154","taxon_label":"Nostoc sp. UHCC-0398","uniprot_accession":"A0A5Q0TWZ6","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["uniprot_pfam_xref"],"pfam_id":"PF19156","protein_label":"MusF2","reviewed":false,"short_name":"DUF5838","source_category":"unclassified","source_mech":"NaturalProductMech","source_path":"data/natural_products/unclassified/muscoride-b.yaml","source_record_id":"naturalproductmech:mibig-f4bf230570","source_record_label":"muscoride B","source_section":"uniprot_accession","taxon_id":"NCBITaxon:2665154","taxon_label":"Nostoc sp. UHCC-0398","uniprot_accession":"A0A5Q0TX00","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF19156","protein_label":"","reviewed":null,"short_name":"DUF5838","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf5838-pf19156.yaml","source_record_id":"Pfam:PF19156","source_record_label":"Family of unknown function (DUF5838)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":30,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"NaturalProductMech":2},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family of unknown function is associated with the biosynthetic gene cluster for anacyclamide A10. The family appears to be restricted to Cyanobacteria. Some matches also contain a methyltransferase domain at the N terminus.","domain_architectures":2,"interpro_id":"IPR031037","known_evidence_count":null,"matches":58,"name":"Family of unknown function (DUF5838)","partial_evidence_count":null,"pfam_id":"PF19156","proteins":58,"proteomes":32,"short_name":"DUF5838","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF19156","structures":12,"taxa":137,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF19156.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":30,"domain_architectures":2,"matches":58,"proteins":58,"proteomes":32,"structures":12,"taxa":137},"curation_status":"SEEDED","description":"This family of unknown function is associated with the biosynthetic gene cluster for anacyclamide A10. The family appears to be restricted to Cyanobacteria. Some matches also contain a methyltransferase domain at the N terminus.","id":"Pfam:PF19156","interpro_id":"InterPro:IPR031037","name":"Family of unknown function (DUF5838)","pfam_id":"PF19156","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF5838","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF19156"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF19156.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"d841c294929a3c6932acb84bc62eda2c1a5c0ad801ceef0ed7201b75beb42d51"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Nostoc sp. UHCC-0398","origins":[{"cited_uniprot_accession":"A0A5Q0TWZ6","commit":"e66f934111777c4ebfe69475d0520c0cfa074785","link_basis":["uniprot_pfam_xref"],"mech":"NaturalProductMech","path":"data/natural_products/amino_acids_and_peptides/muscoride-a.yaml","qualification_status":"NOT_ASSESSED","record_id":"naturalproductmech:mibig-3dbef7a0f0","section":"uniprot_accession","url":"https://github.com/CultureBotAI/NaturalProductMech/blob/e66f934111777c4ebfe69475d0520c0cfa074785/data/natural_products/amino_acids_and_peptides/muscoride-a.yaml"},{"cited_uniprot_accession":"A0A5Q0TWZ6","commit":"e66f934111777c4ebfe69475d0520c0cfa074785","link_basis":["uniprot_pfam_xref"],"mech":"NaturalProductMech","path":"data/natural_products/unclassified/muscoride-b.yaml","qualification_status":"NOT_ASSESSED","record_id":"naturalproductmech:mibig-f4bf230570","section":"uniprot_accession","url":"https://github.com/CultureBotAI/NaturalProductMech/blob/e66f934111777c4ebfe69475d0520c0cfa074785/data/natural_products/unclassified/muscoride-b.yaml"}],"pfam_ids":["PF19156"],"protein_name":"MusF1","registry_status":"NOT_IN_REGISTRY","reviewed":false,"sequence":"MVTYKPIQVDSEPYLEYIGKHKRAFDIYEDLYPVKLFEDFVQVEGRQGGMFRCGCNVTKDELSPARFALFFPTQDDLQLLHNPQQQLEAAFDFFRKVEGRAEVKVNYHLIEKFFGKNPDFRGIYFIAVGVDAQTEISESRLKLFIHLHDAPDKIESAIALCGDSPTLRAFLINNDLLVGFDFYLDGRSEIEVYPTIYQEELQRADIQSRILPLLPPRALPLLKQCEVLQIGFSPANKSNILYFDFVRDSNTFIDNLGNEMAKKVHAYYRHQPVKHVLVGVSEKDLYASSIEKVKLYYFKK","sequence_length":300,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"cbef213da22f6c1d82d64831c3d03981f1401ae8eacba5986fce2fd70057b60d","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A0A5Q0TWZ6.json","taxon_id":"2665154","uniprot_accession":"A0A5Q0TWZ6","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Nostoc sp. UHCC-0398","origins":[{"cited_uniprot_accession":"A0A5Q0TX00","commit":"e66f934111777c4ebfe69475d0520c0cfa074785","link_basis":["uniprot_pfam_xref"],"mech":"NaturalProductMech","path":"data/natural_products/amino_acids_and_peptides/muscoride-a.yaml","qualification_status":"NOT_ASSESSED","record_id":"naturalproductmech:mibig-3dbef7a0f0","section":"uniprot_accession","url":"https://github.com/CultureBotAI/NaturalProductMech/blob/e66f934111777c4ebfe69475d0520c0cfa074785/data/natural_products/amino_acids_and_peptides/muscoride-a.yaml"},{"cited_uniprot_accession":"A0A5Q0TX00","commit":"e66f934111777c4ebfe69475d0520c0cfa074785","link_basis":["uniprot_pfam_xref"],"mech":"NaturalProductMech","path":"data/natural_products/unclassified/muscoride-b.yaml","qualification_status":"NOT_ASSESSED","record_id":"naturalproductmech:mibig-f4bf230570","section":"uniprot_accession","url":"https://github.com/CultureBotAI/NaturalProductMech/blob/e66f934111777c4ebfe69475d0520c0cfa074785/data/natural_products/unclassified/muscoride-b.yaml"}],"pfam_ids":["PF19156"],"protein_name":"MusF2","registry_status":"NOT_IN_REGISTRY","reviewed":false,"sequence":"MVTSNPIQTNSEQYLEYIGKHKLAFDIYEDLYPLKLFEDFVEVEAKKRGLFYILSNVDKDEIYPARFCLRFPSLEEAQLLYNPQQQLQTALNFFRQVESRPEVKLNYHHIQQFFGTISDFQGIVLMAVAIDARTVITESRLKLYIWLKNAPEKVETAIALCGDSPTLRAFLVNDQLQVGFDLFFNGESEIEVYPIISQDELQQFHIRDRIIPLLPPRALPLLQQCAVFQVGFSEANESNILYFDYVHDPNSFVDNLGNEMTKKIHAYYRHQPIKSLTVGIPEHNFYGRAIEHVKLYYDMN","sequence_length":300,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"95d8f20c33159469c0fa2faae78eeb2c9b808b4be47b07cbe731dba53a18b914","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/A0A5Q0TX00.json","taxon_id":"2665154","uniprot_accession":"A0A5Q0TX00","uniprot_release":"2026_03"}],"pfam_id":"PF19156","short_name":"DUF5838","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}