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This domain has a lytic polysaccharide monooxygenase-like (LPMO, [pfam:PF03067]) fold, which are evolutionarily related but have diverged to a different biological function.","domain_architectures":50,"interpro_id":"IPR046530","known_evidence_count":null,"matches":4180,"name":"Copper acquisition factor BIM1-like","partial_evidence_count":null,"pfam_id":"PF20238","proteins":4158,"proteomes":1330,"short_name":"BIM1-like_dom","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF20238","structures":3,"taxa":2901,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF20238.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":3468,"domain_architectures":50,"matches":4180,"proteins":4158,"proteomes":1330,"structures":3,"taxa":2901},"curation_status":"SEEDED","description":"This domain is found in fungal proteins, including copper acquisition factor BIM1 from Cryptococcus neoformans, a cell-surface bound protein that functions in the copper-accumulation pathway shared by the CUF1-dependent copper transporter CTR1 [[cite:PUB00101283],[cite:PUB00101282]]. BIM1 facilitates copper acquisition in the brain of mammalian hosts and acts as a copper-dependent virulence trait in fungal meningitis [[cite:PUB00101283]]. 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