{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF20681","protein_label":"","reviewed":null,"short_name":"DUF6818","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf6818-ipr049203.yaml","source_record_id":"InterPro:IPR049203","source_record_label":"Domain of unknown function DUF6818","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF20681","protein_label":"","reviewed":null,"short_name":"DUF6818","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf6818-pf20681.yaml","source_record_id":"Pfam:PF20681","source_record_label":"Domain of unknown function (DUF6818)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":798,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This presumed domain is functionally uncharacterised. It is found in proteins from eukaryotes, and is typically between 39 and 76 amino acids in length. There are several conserved motifs, Y/FxN, KF and KPTG and a highly conserved W residue at the N-terminal. Structural predictions indicate this domain may fold into three alpha helices.","domain_architectures":9,"interpro_id":"IPR049203","known_evidence_count":null,"matches":887,"name":"Domain of unknown function (DUF6818)","partial_evidence_count":null,"pfam_id":"PF20681","proteins":886,"proteomes":172,"short_name":"DUF6818","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF20681","structures":0,"taxa":489,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF20681.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":798,"domain_architectures":9,"matches":887,"proteins":886,"proteomes":172,"structures":0,"taxa":489},"curation_status":"SEEDED","description":"This presumed domain is functionally uncharacterised. It is found in proteins from eukaryotes, and is typically between 39 and 76 amino acids in length. There are several conserved motifs, Y/FxN, KF and KPTG and a highly conserved W residue at the N-terminal. Structural predictions indicate this domain may fold into three alpha helices.","id":"Pfam:PF20681","interpro_id":"InterPro:IPR049203","name":"Domain of unknown function (DUF6818)","pfam_id":"PF20681","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF6818","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF20681"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF20681.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"908d183a6ac8526a7a989447751fcc06e3d758ae984c8360cdd76e982c0ea480"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF20681","short_name":"DUF6818","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}