{"cross_mech":[],"family":{"alphafold_models":507,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This family, previously known as DUF6983, represents Cyanophage baseplate Pam3 plug gp18 and related proteins. Gp18 has structural similarity to a component of the baseplate Complex for Myoviridae Phage XM1. The cyanophage Pam3 has a substantially simpler molecular organisation than the prototypical, contractile-tail bacteriophage T4, but it retains the essential elements required for DNA injection. The baseplate of Pam3 contains six protein components: the trimeric spike gp20, the trimeric hub gp19, the baseplate wedge (six heterotriplexes of gp22-gp23), the plug of six gp18 monomers, and the fibers (12 trimers of gp24) [[cite:PUB00154413]]. The plug gp18 consists of two-layered beta-sheets and a C-terminal alpha-helix, resembling the immunoglobin fold. Each plug monomer is embedded between the two C-terminal helices of the tube initiator, forming a 'plug' to fix the core helical bundle of the wedge onto the hub [[cite:PUB00154413]]","domain_architectures":6,"interpro_id":"IPR054252","known_evidence_count":null,"matches":1235,"name":"Cyanophage baseplate Pam3 plug gp18","partial_evidence_count":null,"pfam_id":"PF22479","proteins":1235,"proteomes":1081,"short_name":"Pam3_gp18","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF22479","structures":9,"taxa":2192,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF22479.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":507,"domain_architectures":6,"matches":1235,"proteins":1235,"proteomes":1081,"structures":9,"taxa":2192},"curation_status":"SEEDED","description":"This family, previously known as DUF6983, represents Cyanophage baseplate Pam3 plug gp18 and related proteins. Gp18 has structural similarity to a component of the baseplate Complex for Myoviridae Phage XM1. The cyanophage Pam3 has a substantially simpler molecular organisation than the prototypical, contractile-tail bacteriophage T4, but it retains the essential elements required for DNA injection. The baseplate of Pam3 contains six protein components: the trimeric spike gp20, the trimeric hub gp19, the baseplate wedge (six heterotriplexes of gp22-gp23), the plug of six gp18 monomers, and the fibers (12 trimers of gp24) [[cite:PUB00154413]]. The plug gp18 consists of two-layered beta-sheets and a C-terminal alpha-helix, resembling the immunoglobin fold. Each plug monomer is embedded between the two C-terminal helices of the tube initiator, forming a 'plug' to fix the core helical bundle of the wedge onto the hub [[cite:PUB00154413]]","id":"Pfam:PF22479","interpro_id":"InterPro:IPR054252","name":"Cyanophage baseplate Pam3 plug gp18","pfam_id":"PF22479","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"Pam3_gp18","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF22479"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF22479.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"6b3f2cecccf1e0c6beacea138b5c0c54322738f0a35c77ee2b3cd70c353b9914"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF22479","short_name":"Pam3_gp18","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}