{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF23346","protein_label":"Uncharacterized protein C02F5.5","reviewed":true,"short_name":"DUF7087","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf7087-ipr055514.yaml","source_record_id":"InterPro:IPR055514","source_record_label":"Domain of unknown function DUF7087","source_section":"canonical_examples","taxon_id":"NCBITaxon:6239","taxon_label":"Caenorhabditis elegans","uniprot_accession":"P34282","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF23346","protein_label":"","reviewed":null,"short_name":"DUF7087","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf7087-ipr055514.yaml","source_record_id":"InterPro:IPR055514","source_record_label":"Domain of unknown function DUF7087","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF23346","protein_label":"Uncharacterized protein C02F5.5","reviewed":true,"short_name":"DUF7087","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf7087-pf23346.yaml","source_record_id":"Pfam:PF23346","source_record_label":"Integral membrane domain of unknown function (DUF7087)","source_section":"canonical_examples","taxon_id":"NCBITaxon:6239","taxon_label":"Caenorhabditis elegans","uniprot_accession":"P34282","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF23346","protein_label":"","reviewed":null,"short_name":"DUF7087","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf7087-pf23346.yaml","source_record_id":"Pfam:PF23346","source_record_label":"Integral membrane domain of unknown function (DUF7087)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF23346","protein_label":"Uncharacterized protein C02F5.5","reviewed":true,"short_name":"DUF7087","source_category":"sequence/repeat/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/repeat/interpro/duf236-repeat-ipr004296.yaml","source_record_id":"InterPro:IPR004296","source_record_label":"DUF236 repeat","source_section":"canonical_examples","taxon_id":"NCBITaxon:6239","taxon_label":"Caenorhabditis elegans","uniprot_accession":"P34282","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF23346","protein_label":"Uncharacterized protein C02F5.5","reviewed":true,"short_name":"DUF7087","source_category":"sequence/repeat/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/repeat/pfam/duf236-pf03057.yaml","source_record_id":"Pfam:PF03057","source_record_label":"DUF236 repeat","source_section":"canonical_examples","taxon_id":"NCBITaxon:6239","taxon_label":"Caenorhabditis elegans","uniprot_accession":"P34282","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":199,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":1,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":4},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents a four helical integral membrane domain found in nematode species. The function of this domain is unknown.","domain_architectures":9,"interpro_id":"IPR055514","known_evidence_count":null,"matches":219,"name":"Integral membrane domain of unknown function (DUF7087)","partial_evidence_count":null,"pfam_id":"PF23346","proteins":216,"proteomes":74,"short_name":"DUF7087","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF23346","structures":0,"taxa":176,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF23346.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":199,"domain_architectures":9,"matches":219,"proteins":216,"proteomes":74,"structures":0,"taxa":176},"curation_status":"SEEDED","description":"This entry represents a four helical integral membrane domain found in nematode species. The function of this domain is unknown.","id":"Pfam:PF23346","interpro_id":"InterPro:IPR055514","name":"Integral membrane domain of unknown function (DUF7087)","pfam_id":"PF23346","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF7087","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF23346"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF23346.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"71c0c536afb7d48bb6530d3fad4dca92725b1578e1affc28db84a0842ae2ba5b"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Caenorhabditis elegans","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf7087-ipr055514.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR055514","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/domain-of-unknown-function-duf7087-ipr055514.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf7087-pf23346.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF23346","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf7087-pf23346.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/repeat/interpro/duf236-repeat-ipr004296.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR004296","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/repeat/interpro/duf236-repeat-ipr004296.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/repeat/pfam/duf236-pf03057.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF03057","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/repeat/pfam/duf236-pf03057.yaml"}],"pfam_ids":["PF03057","PF23346"],"protein_name":"Uncharacterized protein C02F5.5","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSYMEQIPPYEYYKYVFGTRCAVLACSSFELMMVLLGSLGDSNVLAKLFYLVFLGASAAVSGFNLQQNIDGRDEIKKITGSGDNETRGKAAALVGIPALAAVFVFLCVSGHAFFSLFVLVHVLASIGQLGIEAYEVRNGFCIKAPENKKAVADSYDQNYQILNMVQDSVFDKK","sequence_length":173,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"d647902e6cc98ec50f1a44aec769a2de72b17a2c198e709fa750fcbc110c7638","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P34282.json","taxon_id":"6239","uniprot_accession":"P34282","uniprot_release":"2026_03"}],"pfam_id":"PF23346","short_name":"DUF7087","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}