{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF23447","protein_label":"","reviewed":null,"short_name":"DUF7128","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf7128-ipr055552.yaml","source_record_id":"InterPro:IPR055552","source_record_label":"Domain of unknown function DUF7128","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF23447","protein_label":"","reviewed":null,"short_name":"DUF7128","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf7128-pf23447.yaml","source_record_id":"Pfam:PF23447","source_record_label":"Domain of unknown function (DUF7128)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":170,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain is found in a group of small proteins mainly from Halobacteria. It contains highly conserved cysteine and histidine residues arranged in two CxxC and HxxC motifs that likely coordinate zinc. This domain is predicted to adopt a fold similar to the classical C2H2 and variant C2HC zinc fingers containing beta-hairpin and an alpha helix. In addition, it is predicted to contain an extra N-terminal strand that contributes to the formation of a three-stranded antiparallel beta-sheet. This domain also has a number of highly conserved negatively charged residues.","domain_architectures":1,"interpro_id":"IPR055552","known_evidence_count":null,"matches":176,"name":"Domain of unknown function (DUF7128)","partial_evidence_count":null,"pfam_id":"PF23447","proteins":176,"proteomes":175,"short_name":"DUF7128","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF23447","structures":0,"taxa":342,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF23447.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":170,"domain_architectures":1,"matches":176,"proteins":176,"proteomes":175,"structures":0,"taxa":342},"curation_status":"SEEDED","description":"This domain is found in a group of small proteins mainly from Halobacteria. It contains highly conserved cysteine and histidine residues arranged in two CxxC and HxxC motifs that likely coordinate zinc. This domain is predicted to adopt a fold similar to the classical C2H2 and variant C2HC zinc fingers containing beta-hairpin and an alpha helix. In addition, it is predicted to contain an extra N-terminal strand that contributes to the formation of a three-stranded antiparallel beta-sheet. This domain also has a number of highly conserved negatively charged residues.","id":"Pfam:PF23447","interpro_id":"InterPro:IPR055552","name":"Domain of unknown function (DUF7128)","pfam_id":"PF23447","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF7128","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF23447"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF23447.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"a376dca44b4324787c4a8c6577d16b157ec08d2c62c12f05fd2e83bef561edb9"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF23447","short_name":"DUF7128","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}
