{"cross_mech":[],"family":{"alphafold_models":24,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This protein domain is found in a variety of staphylococcus phage proteins. It was shown to be the antitoxin TscA of a toxin-antitoxin system [[cite:PUB00159162]], with TscT being the toxin [pfam:PF07342]. It is composed of two alpha helices and a beta hairpin and shows weak structural similarity to archaeal prefoldins. Members of this family form a confident homodimer structure with AlphaFold 3 (A0A0H3JR29 iPTM=0.81).","domain_architectures":1,"interpro_id":"IPR055590","known_evidence_count":null,"matches":48,"name":"TscA antitoxin","partial_evidence_count":null,"pfam_id":"PF23767","proteins":48,"proteomes":37,"short_name":"TscA","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF23767","structures":0,"taxa":78,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF23767.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":24,"domain_architectures":1,"matches":48,"proteins":48,"proteomes":37,"structures":0,"taxa":78},"curation_status":"SEEDED","description":"This protein domain is found in a variety of staphylococcus phage proteins. It was shown to be the antitoxin TscA of a toxin-antitoxin system [[cite:PUB00159162]], with TscT being the toxin [pfam:PF07342]. It is composed of two alpha helices and a beta hairpin and shows weak structural similarity to archaeal prefoldins. Members of this family form a confident homodimer structure with AlphaFold 3 (A0A0H3JR29 iPTM=0.81).","id":"Pfam:PF23767","interpro_id":"InterPro:IPR055590","name":"TscA antitoxin","pfam_id":"PF23767","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"TscA","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF23767"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF23767.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"59831d0a22b41fcde4f72801bd09c00933d4b7ec1dcde39fc65fd221de456999"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF23767","short_name":"TscA","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}
