{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF23951","protein_label":"","reviewed":null,"short_name":"DUF7282","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/cell-surface-glycoprotein-1-2-duf7282-ipr055706.yaml","source_record_id":"InterPro:IPR055706","source_record_label":"Cell surface glycoprotein 1/2, DUF7282","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF23951","protein_label":"Cell surface glycoprotein 1","reviewed":true,"short_name":"DUF7282","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf7282-pf23951.yaml","source_record_id":"Pfam:PF23951","source_record_label":"Domain of unknown function (DUF7282)","source_section":"canonical_examples","taxon_id":"NCBITaxon:634497","taxon_label":"Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)","uniprot_accession":"G0HV85","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF23951","protein_label":"Cell surface glycoprotein 2","reviewed":true,"short_name":"DUF7282","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf7282-pf23951.yaml","source_record_id":"Pfam:PF23951","source_record_label":"Domain of unknown function (DUF7282)","source_section":"canonical_examples","taxon_id":"NCBITaxon:634497","taxon_label":"Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)","uniprot_accession":"G0HV86","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF23951","protein_label":"","reviewed":null,"short_name":"DUF7282","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf7282-pf23951.yaml","source_record_id":"Pfam:PF23951","source_record_label":"Domain of unknown function (DUF7282)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF23951","protein_label":"Cell surface glycoprotein 1","reviewed":true,"short_name":"DUF7282","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf7827-pf25162.yaml","source_record_id":"Pfam:PF25162","source_record_label":"Domain of unknown function (DUF7827)","source_section":"canonical_examples","taxon_id":"NCBITaxon:634497","taxon_label":"Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)","uniprot_accession":"G0HV85","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF23951","protein_label":"Cell surface glycoprotein 2","reviewed":true,"short_name":"DUF7282","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf7827-pf25162.yaml","source_record_id":"Pfam:PF25162","source_record_label":"Domain of unknown function (DUF7827)","source_section":"canonical_examples","taxon_id":"NCBITaxon:634497","taxon_label":"Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)","uniprot_accession":"G0HV86","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":false,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF23951","protein_label":"Cell surface glycoprotein 1","reviewed":true,"short_name":"DUF7282","source_category":"sequence/motif/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/motif/pfam/pgf-cterm-pf18204.yaml","source_record_id":"Pfam:PF18204","source_record_label":"PGF-CTERM motif","source_section":"canonical_examples","taxon_id":"NCBITaxon:634497","taxon_label":"Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)","uniprot_accession":"G0HV85","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":910,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":2,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":3},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain is found in uncharacterised bacterial and archaeal proteins. It is predicted to adopt a beta-sandwich with an Ig-like topology, similar to domains members of clan CL0073. Some proteins contain multiple copies of this domain.","domain_architectures":65,"interpro_id":"IPR055706","known_evidence_count":null,"matches":1629,"name":"Domain of unknown function (DUF7282)","partial_evidence_count":null,"pfam_id":"PF23951","proteins":1137,"proteomes":644,"short_name":"DUF7282","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF23951","structures":0,"taxa":1134,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF23951.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":910,"domain_architectures":65,"matches":1629,"proteins":1137,"proteomes":644,"structures":0,"taxa":1134},"curation_status":"SEEDED","description":"This domain is found in uncharacterised bacterial and archaeal proteins. It is predicted to adopt a beta-sandwich with an Ig-like topology, similar to domains members of clan CL0073. Some proteins contain multiple copies of this domain.","id":"Pfam:PF23951","interpro_id":"InterPro:IPR055706","name":"Domain of unknown function (DUF7282)","pfam_id":"PF23951","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF7282","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF23951"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF23951.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"6f3109624b4ee016aecec12c9c2ba31e38a9d0670718abb32341bea74ea1cace"}},"protein_examples":{"candidate_count":2,"discovery_scanned":true,"example_count":2,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf7282-pf23951.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF23951","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf7282-pf23951.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf7827-pf25162.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF25162","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf7827-pf25162.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/motif/pfam/pgf-cterm-pf18204.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF18204","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/motif/pfam/pgf-cterm-pf18204.yaml"}],"pfam_ids":["PF18204","PF23951","PF25162"],"protein_name":"Cell surface glycoprotein 1","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MTDTNEKIRSLFLTALMVFSVFAGTIAFSGGAAAAANVSVQQAAEYDSGTVELALNGSTGSTVNTGDIDIYVDGNKNPSNYGVSSVDTTDDGTTGRLQFSLDQDVQPNRNLTVKVSGLTGGDNTVVAEDIDVTSQTIDADDDSGDTNAFRGEVLAIRADGDTDNDDATSSTKIVVEDSNGAVVTQDTYTANSKVYTYETENLDTGEEYEVSVAGDADENITISNLDLNVNIDDDVGDGANIDDKDTLAVNVSTTRGGEPANATLFNEDDDKVATQVESLKGNENVVFDFGNQSADDSPYYVKVTDNQTGVSAESDQINVSESDDGEASFESSTVQDNIGDVVNITVQVDNTEDAVINIGDENDDNYYIQGQLEDDNGDGEVTVQFNSYTAGNYSDSTVLSVPGDDDIDNIKEGGDYTRGSLSGDTLEAGSYSMNVTAGTSPDVTSPDTVGTLRLNENSVENIQTWAAPSDADIDDDDVDIYDRIGENLTQSDDVAAEDVVVHEIQASGIEGALEYEQEDGSASDVTEAFIAATDTTPYRINDSDATTSGLRLYVNRTDVGANADANPIDFSNSSDAVTVVDDPDNNTYFVAVDTSDVVFENGKTIVKEEDTRLNATFSVREGPLTDDRNSDSAIYTTSERDATLDLDDSGVVTVSAAAGQEVTGETNVAPGSELEVEMESESDANPFVIRPEVDVATDGTYTATADFQDYSAGTNFTVQTLDVDGDSDFSDEEDGRIVEADTATVSISEQESDGSEVVVDSAQLSEGGFIAIHAGNASGDVVGNSEYLGAGSHEDITVTLDEPMDEDFTAVAMPHQDTNGNEAYDFPGDDDPYTQNGSAVTDSANVTIVEEEQTEAPDTETETEAPDTETEEETDAPATDEPATDESETTAAEGPGFTAAIALIALVAAALLAVRRDN","sequence_length":918,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"b490fbe092f18d5ca9f2f307032efcb6a8b7c001cddfd97e5477bc179956dccd","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/G0HV85.json","taxon_id":"634497","uniprot_accession":"G0HV85","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Haloarcula hispanica (strain ATCC 33960 / DSM 4426 / JCM 8911 / NBRC 102182 / NCIMB 2187 / VKM B-1755)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf7282-pf23951.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF23951","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf7282-pf23951.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf7827-pf25162.yaml","qualification_status":"NOT_ASSESSED","record_id":"Pfam:PF25162","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf7827-pf25162.yaml"}],"pfam_ids":["PF18204","PF23951","PF25162"],"protein_name":"Cell surface glycoprotein 2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MTGNSDKVRSLFLTALMVFSVFAGTIAFSGGAAAAANVSVQQAAEYDSGTVELALNGSTGSPVTTGDINIYIDGNENPSNYGVSSVDTTDDGTTGRLQFSLDQDVQPNRNLTVEVSGLTGGDNTVVAEDIDVTSQTIDADDDSGDTNAFRGEVLAIRADGGEGDADDATSSTQIVVEDSNGAVVTQDTYTANSKVYTYETENLDTGEEYEVTVGGTADENITISNLDLNVNIDDDVGDGANIDDTDTLAVNVSTTRGGEPANATLFNEDDDKVATQIKSLKGNENVVFDFGNQSADDSPYYVKVTDNQTGVSAESDQINVSESGEGDASFETSTVQDEVGDVTNITVQMGNTENAVINVGSQNDDNYVIQGQLEDDNGDGEVTVQFNSYTAGTDNNNTVLTVPGDDDLDEVEEKGSFTDSRNSLDEDVLEPQSYSINVTAGTSPDVTSPDTVGTLRLNENSVESMQTWVAPSDADIDDEDIDIYDRIGENLTQSDDVAVEDVVVHEIQASGIEGALEYEQEDNGSSDVTDAFIAAADTTPDRINDDTSASGLQLYVNRTDVGANADADPINFANSSSAVTVVDDPDNNTYFVALDTEDVEFESGNTITEEEDTEINATFSVQEGPLTDDSSSESELYTTSERNAELNLDDDGFVTVGAAAGQTVSGDTNVAPGSELEVEMESESEANPFVERPEATVGPNGTYVATEDFSDYSAGTNFTVQTLDVDGDSDFSDEEDGRIVEADTATVSISDQESDGSEVVVDSAQLSSGGFIAIHAGDASGDVVGNSEYLEAGTYNDLTITLDEPMDENFTAVAMPHQDTNGNEEYDFPGDDGPYTQNGSAVTDSANVTVSAEEPEDTPEDTPEDTPEDTPEDTPEDTPADTPEDTPDTGTETTEAEGPGFTAAIALIALVAAALLAVRRDN","sequence_length":922,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"76fb66de5c81e833c13326d3e46c5013a88dc823cee711ba96b1763f2e922a8b","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/G0HV86.json","taxon_id":"634497","uniprot_accession":"G0HV86","uniprot_release":"2026_03"}],"pfam_id":"PF23951","short_name":"DUF7282","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}