{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF24219","protein_label":"Uncharacterized 7.2 kDa protein in tk-vs intergenic region","reviewed":true,"short_name":"DUF7438","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf7438-pf24219.yaml","source_record_id":"Pfam:PF24219","source_record_label":"Family of unknown function (DUF7438)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10665","taxon_label":"Enterobacteria phage T4","uniprot_accession":"P13306","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF24219","protein_label":"Uncharacterized 7.1 kDa protein in tk-vs intergenic region","reviewed":true,"short_name":"DUF7438","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf7438-pf24219.yaml","source_record_id":"Pfam:PF24219","source_record_label":"Family of unknown function (DUF7438)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10665","taxon_label":"Enterobacteria phage T4","uniprot_accession":"P13307","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF24219","protein_label":"Uncharacterized 7.6 kDa protein in mobD-ri intergenic region","reviewed":true,"short_name":"DUF7438","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf7438-pf24219.yaml","source_record_id":"Pfam:PF24219","source_record_label":"Family of unknown function (DUF7438)","source_section":"canonical_examples","taxon_id":"NCBITaxon:10665","taxon_label":"Enterobacteria phage T4","uniprot_accession":"P39238","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF24219","protein_label":"","reviewed":null,"short_name":"DUF7438","source_category":"sequence/family/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/family/pfam/duf7438-pf24219.yaml","source_record_id":"Pfam:PF24219","source_record_label":"Family of unknown function (DUF7438)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":29,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":3,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents a family of uncharacterized proteins found in bacteriophages. The function of this protein family is currently unknown. The family appears to be conserved across various phage species that infect Escherichia coli and related bacteria. The family includes members from Phage T2, T4 and T6. Members of this family are typically short proteins of around 60-67 amino acids in length. Bacteriophage T4 contains four proteins that belong to this family. The structure of these proteins is predicted to be composed of two alpha helices that pack together. Structure prediction suggests these proteins may homodimerise (iPTM=0.83).","domain_architectures":1,"interpro_id":"IPR055861","known_evidence_count":null,"matches":536,"name":"Family of unknown function (DUF7438)","partial_evidence_count":null,"pfam_id":"PF24219","proteins":536,"proteomes":185,"short_name":"DUF7438","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF24219","structures":0,"taxa":414,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF24219.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":29,"domain_architectures":1,"matches":536,"proteins":536,"proteomes":185,"structures":0,"taxa":414},"curation_status":"SEEDED","description":"This entry represents a family of uncharacterized proteins found in bacteriophages. The function of this protein family is currently unknown. The family appears to be conserved across various phage species that infect Escherichia coli and related bacteria. The family includes members from Phage T2, T4 and T6. Members of this family are typically short proteins of around 60-67 amino acids in length. Bacteriophage T4 contains four proteins that belong to this family. The structure of these proteins is predicted to be composed of two alpha helices that pack together. Structure prediction suggests these proteins may homodimerise (iPTM=0.83).","id":"Pfam:PF24219","interpro_id":"InterPro:IPR055861","name":"Family of unknown function (DUF7438)","pfam_id":"PF24219","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF7438","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF24219"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF24219.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"bd8c08fcd872aa88f5d5e531023e0a5569733c60080141f78b4e8c508fdd5128"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Enterobacteria phage T4","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf7438-pf24219.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF24219","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf7438-pf24219.yaml"}],"pfam_ids":["PF24219"],"protein_name":"Uncharacterized 7.2 kDa protein in tk-vs intergenic region","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MITREQKNEILFLVGEIISLEKDLSFEISSEYGDAETYYELVKSIDKAENDLETYLENLTKD","sequence_length":62,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"fc18e8c49d378823c0ca4c5a874fbfe59b7895457d8edd3c51bc6b2ea7a6ac41","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P13306.json","taxon_id":"10665","uniprot_accession":"P13306","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Enterobacteria phage T4","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf7438-pf24219.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF24219","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf7438-pf24219.yaml"}],"pfam_ids":["PF24219"],"protein_name":"Uncharacterized 7.1 kDa protein in tk-vs intergenic region","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MSLSKEQKDTLFSLIHEVMDKNSELEKVCNECGPFSANEYEELSKEFDNKEQELIDYINSL","sequence_length":61,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"4bff18d1d418561c293f3fb133b8226e83a9a47e6dba42eacbe378945a5df6c7","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P13307.json","taxon_id":"10665","uniprot_accession":"P13307","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Enterobacteria phage T4","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/family/pfam/duf7438-pf24219.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF24219","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/family/pfam/duf7438-pf24219.yaml"}],"pfam_ids":["PF24219"],"protein_name":"Uncharacterized 7.6 kDa protein in mobD-ri intergenic region","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MLTREQFEKIIKLAHDIEIDSYQLAVEHCEGYSYDGIEAAKRDLDKSKAKLVQYLEMIRWNNEN","sequence_length":64,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"05b9e60d0b894cc3543a271207cb6efcbd24fb192a0d943f569799fbe8d51b26","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P39238.json","taxon_id":"10665","uniprot_accession":"P39238","uniprot_release":"2026_03"}],"pfam_id":"PF24219","short_name":"DUF7438","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}