{"cross_mech":[],"family":{"alphafold_models":210,"candidate_reasons":["pfam_previous_unknown_name"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":false,"records_by_mech":{},"scanned":false},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents a family of uncharacterised integral membrane proteins found in DNA viruses that infect archaea and halobacteria, incuding Matrix protein Halorubrum pleomorphic virus 1 (VP3). These proteins contain four predicted transmembrane helices. These proteins have a pair of beta hairpin structures inserted between the first and second alpha helices. There is some evidence that this beta hairpin may mediate a homodimerisation interaction (AlphaFold3 W0JNP7 ipTM=0.7 pTM=0.74).","domain_architectures":2,"interpro_id":"IPR058336","known_evidence_count":null,"matches":254,"name":"VP3-like","partial_evidence_count":null,"pfam_id":"PF26064","proteins":252,"proteomes":171,"short_name":"VP3","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26064","structures":0,"taxa":352,"unknown_status":"EX_DUF"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF26064.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":210,"domain_architectures":2,"matches":254,"proteins":252,"proteomes":171,"structures":0,"taxa":352},"curation_status":"SEEDED","description":"This entry represents a family of uncharacterised integral membrane proteins found in DNA viruses that infect archaea and halobacteria, incuding Matrix protein Halorubrum pleomorphic virus 1 (VP3). These proteins contain four predicted transmembrane helices. These proteins have a pair of beta hairpin structures inserted between the first and second alpha helices. There is some evidence that this beta hairpin may mediate a homodimerisation interaction (AlphaFold3 W0JNP7 ipTM=0.7 pTM=0.74).","id":"Pfam:PF26064","interpro_id":"InterPro:IPR058336","name":"VP3-like","pfam_id":"PF26064","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"EX_DUF","short_name":"VP3","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26064"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF26064.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"d280846df2a68b51a93a16018e6c7664b4c8210af015231fe032c019b0bc495f"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF26064","short_name":"VP3","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}