{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF26357","protein_label":"","reviewed":null,"short_name":"DUF8092","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf8092-ipr058405.yaml","source_record_id":"InterPro:IPR058405","source_record_label":"Domain of unknown function DUF8092","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF26357","protein_label":"Uncharacterized protein Mb0967","reviewed":true,"short_name":"DUF8092","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8092-pf26357.yaml","source_record_id":"Pfam:PF26357","source_record_label":"Domain of unknown function (DUF8092)","source_section":"canonical_examples","taxon_id":"NCBITaxon:233413","taxon_label":"Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)","uniprot_accession":"P64764","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF26357","protein_label":"Uncharacterized protein MT0968.2","reviewed":true,"short_name":"DUF8092","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8092-pf26357.yaml","source_record_id":"Pfam:PF26357","source_record_label":"Domain of unknown function (DUF8092)","source_section":"canonical_examples","taxon_id":"NCBITaxon:83331","taxon_label":"Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)","uniprot_accession":"P9WKN8","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF26357","protein_label":"Uncharacterized protein Rv0942","reviewed":true,"short_name":"DUF8092","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8092-pf26357.yaml","source_record_id":"Pfam:PF26357","source_record_label":"Domain of unknown function (DUF8092)","source_section":"canonical_examples","taxon_id":"NCBITaxon:83332","taxon_label":"Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)","uniprot_accession":"P9WKN9","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF26357","protein_label":"","reviewed":null,"short_name":"DUF8092","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8092-pf26357.yaml","source_record_id":"Pfam:PF26357","source_record_label":"Domain of unknown function (DUF8092)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":4,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":3,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":1},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents a domain of unknown function (DUF8092) found exclusively in members of the Mycobacterium tuberculosis complex. The domain is approximately 54 amino acids in length and is highly conserved across all known members. The function of this domain has not been experimentally determined.","domain_architectures":1,"interpro_id":"IPR058405","known_evidence_count":null,"matches":7,"name":"Domain of unknown function (DUF8092)","partial_evidence_count":null,"pfam_id":"PF26357","proteins":7,"proteomes":7,"short_name":"DUF8092","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26357","structures":0,"taxa":19,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF26357.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":4,"domain_architectures":1,"matches":7,"proteins":7,"proteomes":7,"structures":0,"taxa":19},"curation_status":"SEEDED","description":"This entry represents a domain of unknown function (DUF8092) found exclusively in members of the Mycobacterium tuberculosis complex. The domain is approximately 54 amino acids in length and is highly conserved across all known members. The function of this domain has not been experimentally determined.","id":"Pfam:PF26357","interpro_id":"InterPro:IPR058405","name":"Domain of unknown function (DUF8092)","pfam_id":"PF26357","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF8092","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26357"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF26357.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"00d355ffd680bbdf8a3f9cdde7b885cd7c23a4ce874bdaf99a47f7b5fb98f5bd"}},"protein_examples":{"candidate_count":3,"discovery_scanned":true,"example_count":3,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf8092-pf26357.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF26357","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf8092-pf26357.yaml"}],"pfam_ids":["PF26357"],"protein_name":"Uncharacterized protein Mb0967","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGRSATIAMVPKRRDAMNRHSGPILSSGFIASSSNSCPANSLRMPSALAAETLSFDDRAVRRSTHHPGGGYPQKHAINLQSGLCPAYANASR","sequence_length":92,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"070bae23c51b7d1be0524750cf4af2e8237a68788f8744d9d41c68b533c2da73","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P64764.json","taxon_id":"233413","uniprot_accession":"P64764","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf8092-pf26357.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF26357","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf8092-pf26357.yaml"}],"pfam_ids":["PF26357"],"protein_name":"Uncharacterized protein MT0968.2","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGRSATIAMVPKRRDAMNRHSGPILSSGFIASSSNSCPANSLRMPSALAAETLSFDDRAVRRSTHHPGGGYPQKHAINLQSGLCPAYANASR","sequence_length":92,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"070bae23c51b7d1be0524750cf4af2e8237a68788f8744d9d41c68b533c2da73","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P9WKN8.json","taxon_id":"83331","uniprot_accession":"P9WKN8","uniprot_release":"2026_03"},{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf8092-pf26357.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF26357","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf8092-pf26357.yaml"}],"pfam_ids":["PF26357"],"protein_name":"Uncharacterized protein Rv0942","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MGRSATIAMVPKRRDAMNRHSGPILSSGFIASSSNSCPANSLRMPSALAAETLSFDDRAVRRSTHHPGGGYPQKHAINLQSGLCPAYANASR","sequence_length":92,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"070bae23c51b7d1be0524750cf4af2e8237a68788f8744d9d41c68b533c2da73","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P9WKN9.json","taxon_id":"83332","uniprot_accession":"P9WKN9","uniprot_release":"2026_03"}],"pfam_id":"PF26357","short_name":"DUF8092","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}