{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF26590","protein_label":"","reviewed":null,"short_name":"DUF8186_M","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/protein-of-unknown-function-duf8186-central-domain-ipr058910.yaml","source_record_id":"InterPro:IPR058910","source_record_label":"Protein of unknown function DUF8186, central domain","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF26590","protein_label":"","reviewed":null,"short_name":"DUF8186_M","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8186-m-pf26590.yaml","source_record_id":"Pfam:PF26590","source_record_label":"Domain of unknown function (DUF8186) central domain","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":236,"candidate_reasons":["name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents the central domain found in a family of uncharacterised proteins from archaea. The proteins are predominantly found in the Halobacteria class, which includes members of the Haloferacaceae, Haloarculaceae, and Natrialbaceae families. The proteins in this family are typically around 550-580 amino acids in length.","domain_architectures":3,"interpro_id":"IPR058910","known_evidence_count":null,"matches":260,"name":"Domain of unknown function (DUF8186) central domain","partial_evidence_count":null,"pfam_id":"PF26590","proteins":260,"proteomes":156,"short_name":"DUF8186_M","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26590","structures":0,"taxa":259,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF26590.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":236,"domain_architectures":3,"matches":260,"proteins":260,"proteomes":156,"structures":0,"taxa":259},"curation_status":"SEEDED","description":"This entry represents the central domain found in a family of uncharacterised proteins from archaea. The proteins are predominantly found in the Halobacteria class, which includes members of the Haloferacaceae, Haloarculaceae, and Natrialbaceae families. The proteins in this family are typically around 550-580 amino acids in length.","id":"Pfam:PF26590","interpro_id":"InterPro:IPR058910","name":"Domain of unknown function (DUF8186) central domain","pfam_id":"PF26590","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF8186_M","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26590"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF26590.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"bba5bf6e1e6f939d34a415715dc2bea068f4eee44e8749a6db6f8e116656641b"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF26590","short_name":"DUF8186_M","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}
