{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF26731","protein_label":"","reviewed":null,"short_name":"DUF8243","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf8243-ipr059287.yaml","source_record_id":"InterPro:IPR059287","source_record_label":"Domain of unknown function DUF8243","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF26731","protein_label":"","reviewed":null,"short_name":"DUF8243","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8243-pf26731.yaml","source_record_id":"Pfam:PF26731","source_record_label":"Domain of unknown function (DUF8243)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":255,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain is found in uncharacterised proteins. It contains two pairs of highly conserved cysteine residues that may coordinate a metal ion. This domain is predicted to fold into a structure that is probably distantly related to domains with beta-tent fold (CL0080). The zinc ribbon in this domain is grafted into alpha/beta core.","domain_architectures":4,"interpro_id":"IPR059287","known_evidence_count":null,"matches":334,"name":"Domain of unknown function (DUF8243)","partial_evidence_count":null,"pfam_id":"PF26731","proteins":334,"proteomes":267,"short_name":"DUF8243","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26731","structures":0,"taxa":646,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF26731.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":255,"domain_architectures":4,"matches":334,"proteins":334,"proteomes":267,"structures":0,"taxa":646},"curation_status":"SEEDED","description":"This domain is found in uncharacterised proteins. It contains two pairs of highly conserved cysteine residues that may coordinate a metal ion. This domain is predicted to fold into a structure that is probably distantly related to domains with beta-tent fold (CL0080). The zinc ribbon in this domain is grafted into alpha/beta core.","id":"Pfam:PF26731","interpro_id":"InterPro:IPR059287","name":"Domain of unknown function (DUF8243)","pfam_id":"PF26731","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF8243","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26731"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF26731.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"ba79e1729061a0211cc77fdc64223dd8e99e3aa1d60285993aab0950b41e4ba4"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF26731","short_name":"DUF8243","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}