{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF26740","protein_label":"Uncharacterized protein At4g37920","reviewed":true,"short_name":"DUF8246","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf8246-ipr059290.yaml","source_record_id":"InterPro:IPR059290","source_record_label":"Domain of unknown function DUF8246","source_section":"canonical_examples","taxon_id":"NCBITaxon:3702","taxon_label":"Arabidopsis thaliana","uniprot_accession":"Q84WN0","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF26740","protein_label":"","reviewed":null,"short_name":"DUF8246","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf8246-ipr059290.yaml","source_record_id":"InterPro:IPR059290","source_record_label":"Domain of unknown function DUF8246","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":true,"link_basis":["canonical_example_family_classification"],"pfam_id":"PF26740","protein_label":"Uncharacterized protein At4g37920","reviewed":true,"short_name":"DUF8246","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8246-pf26740.yaml","source_record_id":"Pfam:PF26740","source_record_label":"Domain of unknown function (DUF8246)","source_section":"canonical_examples","taxon_id":"NCBITaxon:3702","taxon_label":"Arabidopsis thaliana","uniprot_accession":"Q84WN0","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF26740","protein_label":"","reviewed":null,"short_name":"DUF8246","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8246-pf26740.yaml","source_record_id":"Pfam:PF26740","source_record_label":"Domain of unknown function (DUF8246)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":964,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","description_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":1,"protein_traits_record":true,"records_by_mech":{"ProteinTraitsMech":2},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This domain is found in the uncharacterised protein At4g37920 from Arabidopsis thaliana and similar proteins. This domain is predicted to adopt an all-alpha configuration. Its specific function is unknown.","domain_architectures":45,"interpro_id":"IPR059290","known_evidence_count":null,"matches":1195,"name":"Domain of unknown function (DUF8246)","partial_evidence_count":null,"pfam_id":"PF26740","proteins":1182,"proteomes":420,"short_name":"DUF8246","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26740","structures":0,"taxa":1161,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF26740.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":964,"domain_architectures":45,"matches":1195,"proteins":1182,"proteomes":420,"structures":0,"taxa":1161},"curation_status":"SEEDED","description":"This domain is found in the uncharacterised protein At4g37920 from Arabidopsis thaliana and similar proteins. This domain is predicted to adopt an all-alpha configuration. Its specific function is unknown.","id":"Pfam:PF26740","interpro_id":"InterPro:IPR059290","name":"Domain of unknown function (DUF8246)","pfam_id":"PF26740","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF8246","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF26740"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF26740.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"cd2ece05b1d322727d728ab46781ab24d38020de5feb1fa2a11859d63e94e0ea"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Arabidopsis thaliana","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf8246-ipr059290.yaml","qualification_status":"NOT_ASSESSED","record_id":"InterPro:IPR059290","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/interpro/domain-of-unknown-function-duf8246-ipr059290.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["canonical_example_family_classification","ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf8246-pf26740.yaml","qualification_status":"LEGACY_OR_UNSPECIFIED","record_id":"Pfam:PF26740","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf8246-pf26740.yaml"}],"pfam_ids":["PF26740","PF30870","PF30872"],"protein_name":"Uncharacterized protein At4g37920","registry_status":"NOT_IN_REGISTRY","reviewed":true,"sequence":"MANLLETSIFFSSADKLLSFPPKNSQTHHLPFSAFINGGRKIRKSSTITFATDTVTYNGTTSAEVKSSVEDPMEVEVAEGYTMAQFCDKIIDLFLNEKPKVKQWKTYLVLRDEWNKYSVNFYKRCRIRADTETDPILKQKLVSLESKVKKIDKEMEKHNDLLKEIQENPTDINAIAAKRRRDFTGEFFRYVTLLSETLDGLEDRDAVARLATRCLSAVSAYDNTLESVETLDTAQAKFEDILNSPSVDSACEKIRSLAKAKELDSSLILLINSAYAAAKESQTVTNEAKDIMYHLYKATKSSLRSITPKEIKLLKYLLNITDPEERFSALATAFSPGDDHEAKDPKALYTTPKELHKWIKIMLDAYHLNKEETDIKEAKQMSQPIVIQRLFILKDTIEDEYLDKKTIVADETPKKEEEDTTIEDFLN","sequence_length":427,"sequence_origin":"UNIPROT_FETCH","sequence_sha256":"4c5dcea873bb7e39a35f761ce0581910d4880fe623d25051cc7e93041b89addd","sequence_version":2,"source_url":"https://rest.uniprot.org/uniprotkb/Q84WN0.json","taxon_id":"3702","uniprot_accession":"Q84WN0","uniprot_release":"2026_03"}],"pfam_id":"PF26740","short_name":"DUF8246","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}