{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF30639","protein_label":"","reviewed":null,"short_name":"DUF8684","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf8684-ipr061745.yaml","source_record_id":"InterPro:IPR061745","source_record_label":"Domain of unknown function DUF8684","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF30639","protein_label":"","reviewed":null,"short_name":"DUF8684","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8684-pf30639.yaml","source_record_id":"Pfam:PF30639","source_record_label":"Domain of unknown function (DUF8684)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":2691,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents an N-terminal domain found in biotin carboxyl carrier protein of acetyl-CoA carboxylase proteins. Structure prediction suggests this domain may mediate homodimerisation.","domain_architectures":4,"interpro_id":"IPR061745","known_evidence_count":null,"matches":4142,"name":"Domain of unknown function (DUF8684)","partial_evidence_count":null,"pfam_id":"PF30639","proteins":4142,"proteomes":4103,"short_name":"DUF8684","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF30639","structures":1,"taxa":5514,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF30639.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":2691,"domain_architectures":4,"matches":4142,"proteins":4142,"proteomes":4103,"structures":1,"taxa":5514},"curation_status":"SEEDED","description":"This entry represents an N-terminal domain found in biotin carboxyl carrier protein of acetyl-CoA carboxylase proteins. Structure prediction suggests this domain may mediate homodimerisation.","id":"Pfam:PF30639","interpro_id":"InterPro:IPR061745","name":"Domain of unknown function (DUF8684)","pfam_id":"PF30639","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF8684","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF30639"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF30639.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"0c4a4b901fb649d63f546dca314f224cc106fb8c449bcab9506d01d2063c7f37"}},"protein_examples":{"candidate_count":1,"discovery_scanned":true,"example_count":1,"examples":[{"evidence_scope":"FAMILY_MEMBERSHIP_NOT_FUNCTION","organism":"Escherichia coli (strain K12)","origins":[{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_own_pfam_record_example"],"mech":"ProteinTraitsMech","path":"data/traits/sequence/domain/pfam/duf8684-pf30639.yaml","qualification_status":"QUALIFIED","record_id":"Pfam:PF30639","section":"canonical_examples","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/traits/sequence/domain/pfam/duf8684-pf30639.yaml"},{"cited_uniprot_accession":"","commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","link_basis":["ptm_registry_exact_uniprot_pfam_xref"],"mech":"ProteinTraitsMech","path":"data/grounding/protein_registry.jsonl","qualification_status":"NOT_ASSESSED_FOR_THIS_FAMILY","record_id":"UniProtKB:P0ABD8","section":"protein_registry","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"}],"pfam_ids":["PF00364","PF30639"],"protein_name":"Biotin carboxyl carrier protein of acetyl-CoA carboxylase","registry_source":{"commit":"70edd6f8458845f7d7783ac4f416df519f5e1de6","path":"data/grounding/protein_registry.jsonl","repository":"https://github.com/CultureBotAI/proteintraitsmech","sequence_sha256":"ec64b1fae668cecf3d3f8c0737c990a9152e06a334a351bcd807df0d1d69808e","sequence_version":1,"sha256":"1be0cf02b76b03a8fe9b80bcead9cd4a419157116eb8da038f266bcc33015eb9","uniprot_release":"2026_03","url":"https://github.com/CultureBotAI/proteintraitsmech/blob/70edd6f8458845f7d7783ac4f416df519f5e1de6/data/grounding/protein_registry.jsonl"},"registry_status":"EXACT_SEQUENCE_VERSION_MATCH","reviewed":true,"sequence":"MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVMQQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAFIEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE","sequence_length":156,"sequence_origin":"PTM_REGISTRY_MIRROR","sequence_sha256":"ec64b1fae668cecf3d3f8c0737c990a9152e06a334a351bcd807df0d1d69808e","sequence_version":1,"source_url":"https://rest.uniprot.org/uniprotkb/P0ABD8.json","taxon_id":"83333","uniprot_accession":"P0ABD8","uniprot_release":"2026_03"}],"pfam_id":"PF30639","short_name":"DUF8684","status":"HAS_SEQUENCE_EXAMPLE","unresolved":[]}}