{"cross_mech":[{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF31103","protein_label":"","reviewed":null,"short_name":"DUF8808","source_category":"sequence/domain/interpro","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/interpro/domain-of-unknown-function-duf8808-ipr061869.yaml","source_record_id":"InterPro:IPR061869","source_record_label":"Domain of unknown function DUF8808","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"},{"cited_uniprot_accession":"","family_mentioned_in_record":null,"link_basis":["trait_identifier"],"pfam_id":"PF31103","protein_label":"","reviewed":null,"short_name":"DUF8808","source_category":"sequence/domain/pfam","source_mech":"ProteinTraitsMech","source_path":"data/traits/sequence/domain/pfam/duf8808-pf31103.yaml","source_record_id":"Pfam:PF31103","source_record_label":"Domain of unknown function (DUF8808)","source_section":"trait_identifier","taxon_id":"","taxon_label":"","uniprot_accession":"","unknown_status":"UNKNOWN_CANDIDATE"}],"family":{"alphafold_models":412,"candidate_reasons":["short_name_matches_duf","name_says_unknown_function","domain_of_unknown_function"],"characterization_status":"","context_evidence_count":null,"cross_mech":{"example_proteins":0,"protein_traits_record":true,"records_by_mech":{},"scanned":true},"curation_status":"SEEDED","demotion_reasons":[],"description":"This entry represents a domain of approximately 220 residues found in bacteria, predominantly Proteobacteria. This domain is typically located N-terminal to HNH nuclease domains ([pfam:PF13395]). Some proteins containing this domain also possess methyltransferase domains, suggesting a role in restriction-modification systems. The function of this domain remains to be determined.","domain_architectures":16,"interpro_id":"IPR061869","known_evidence_count":null,"matches":658,"name":"Domain of unknown function (DUF8808)","partial_evidence_count":null,"pfam_id":"PF31103","proteins":658,"proteomes":628,"short_name":"DUF8808","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF31103","structures":0,"taxa":1188,"unknown_status":"UNKNOWN_CANDIDATE"},"inputs":{"cross_mech":"cross-mech-duf-examples-2026-10-10","members":"pfam-uniprot-uniref90-2026-10-07","protein_examples":"duf-protein-examples-2026-10-13","worklist":"interpro-pfam-duf-2026-10-10"},"members":[],"metadata":{"curation_status":"SEEDED","local_source":"source/data/families/PF31103.yaml","record":{"characterization_status":"UNSCORED","counters":{"alphafold_models":412,"domain_architectures":16,"matches":658,"proteins":658,"proteomes":628,"structures":0,"taxa":1188},"curation_status":"SEEDED","description":"This entry represents a domain of approximately 220 residues found in bacteria, predominantly Proteobacteria. This domain is typically located N-terminal to HNH nuclease domains ([pfam:PF13395]). Some proteins containing this domain also possess methyltransferase domains, suggesting a role in restriction-modification systems. The function of this domain remains to be determined.","id":"Pfam:PF31103","interpro_id":"InterPro:IPR061869","name":"Domain of unknown function (DUF8808)","pfam_id":"PF31103","provenance":{"generated_at":"2026-10-10T07:44:21.614711Z","path":"data/worklists/interpro-pfam-duf-2026-10-10.json","sha256":"17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383","snapshot_id":"interpro-pfam-duf-2026-10-10","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/"},"seed_status":"UNKNOWN_CANDIDATE","short_name":"DUF8808","source_url":"https://www.ebi.ac.uk/interpro/api/entry/pfam/PF31103"},"source":{"commit":"c8155abfcf881ad8662936343deb81e604e3a194","path":"data/families/PF31103.yaml","repository":"https://github.com/CultureBotAI/DUFMech","sha256":"f8413e38ed28fa0462fd79bef4bb49c728c075104b540a8958b52c5db622c9a7"}},"protein_examples":{"candidate_count":0,"discovery_scanned":true,"example_count":0,"examples":[],"pfam_id":"PF31103","short_name":"DUF8808","status":"NO_SIBLING_CANDIDATE","unresolved":[]}}