id: Pfam:PF01042
pfam_id: PF01042
name: Endoribonuclease L-PSP
short_name: Ribonuc_L-PSP
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01042
counters:
  proteins: 74014
  matches: 76763
  proteomes: 19722
  taxa: 31830
  structures: 76
  alphafold_models: 48953
  domain_architectures: 403
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR006175
description: Endoribonuclease active on single-stranded mRNA. Inhibits protein synthesis by cleavage of
  mRNA [[cite:PUB00007949]]. Previously thought to inhibit protein synthesis initiation [[cite:PUB00002939]].
  This protein may also be involved in the regulation of purine biosynthesis [[cite:PUB00007948]]. YjgF
  (renamed RidA) family members are enamine/imine deaminases. They hydrolyze reactive intermediates released
  by PLP-dependent enzymes, including threonine dehydratase [[cite:PUB00064878]]. YjgF also prevents inhibition
  of transaminase B (IlvE) in Salmonella [[cite:PUB00109184]].