id: Pfam:PF01139
pfam_id: PF01139
name: tRNA-splicing ligase RtcB
short_name: RtcB
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01139
counters:
  proteins: 12598
  matches: 15105
  proteomes: 9357
  taxa: 17245
  structures: 20
  alphafold_models: 8370
  domain_architectures: 66
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR001233
description: This family of RNA ligases ([ec:6.5.1.3]) join 2',3'-cyclic phosphate and 5'-OH ends. They
  catalyse the splicing of tRNA and may also participate in tRNA repair and recovery from stress-induced
  RNA damage [[cite:PUB00152168],[cite:PUB00057853],[cite:PUB00056744]].