id: Pfam:PF01724
pfam_id: PF01724
name: Domain of unknown function DUF29
short_name: DUF29
seed_status: UNKNOWN_CANDIDATE
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01724
counters:
  proteins: 4280
  matches: 4280
  proteomes: 791
  taxa: 1622
  structures: 1
  alphafold_models: 2600
  domain_architectures: 11
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR002636
description: This family consists of various hypothetical proteins from cyanobacteria, none of which are
  functionally described. The aligned region is approximately 120-140 amino acids long corresponding to
  almost the entire length of the proteins in the family. [swissprot:Q2RPE2], PDB:3fcn, is a small protein
  that has a novel all-alpha fold. The N-terminal helical hairpin is likely to function as a dimerisation
  module. This protein is a member of PFam family PF01724. The function of this protein is unknown. One
  protein sequence contains a fusion of this protein and a DnaB domain, suggesting a possible role in
  DNA helicase activity (hypothetical). Dali hits have low Z and high rmsd, suggesting probably only topological
  similarities (not functional relevance) (details derived from TOPSAN). The family has several highly
  conserved sequence motifs, including YD/ExD, DxxNVxEEIE, and CPY/F/W, as well as conserved tryptophans.