id: Pfam:PF01895
pfam_id: PF01895
name: PhoU domain
short_name: PhoU
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01895
counters:
  proteins: 24850
  matches: 45912
  proteomes: 15876
  taxa: 22728
  structures: 10
  alphafold_models: 16970
  domain_architectures: 44
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR026022
description: This family contains phosphate regulatory proteins including PhoU. PhoU proteins are known
  to play a role in the regulation of phosphate uptake. The PhoU domain is composed of a three helix bundle
  [[cite:PUB00031207]]. The PhoU protein contains two copies of this domain. The domain binds to an iron
  cluster via its conserved E/DXXXD motif.