id: Pfam:PF01937
pfam_id: PF01937
name: Damage-control phosphatase ARMT1-like domain
short_name: ARMT1-like_dom
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01937
counters:
  proteins: 9217
  matches: 9512
  proteomes: 4951
  taxa: 11762
  structures: 16
  alphafold_models: 7564
  domain_architectures: 110
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR002791
description: This domain is widely distributed in all domains of life and occur in stand-alone form and
  as C-terminal fusions to pantothenate kinase (PanK) in plants and animals. They are metal-dependent
  phosphatases involved in metabolic damage-control processes termed "damage pre-emption" or "housecleaning".
  S.cerevisiae Damage-control phosphatase YMR027W and the human orthologue Damage-control phosphatase
  ARMT1 (also known as C6orf211) are involved in response to DNA damage, a damage pre-emption function.
  Crystal structure of Damage-control phosphatase At2g17340 from Arabidopsis revealed a novel protein
  fold and several conserved residues coordinating a metal ion (probably Mg2+), which exhibits a high
  degree of conservation, suggesting that the metal-binding site is central for the function [[cite:PUB00088733]].