id: Pfam:PF01954
pfam_id: PF01954
name: AF2212-like
short_name: AF2212-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01954
counters:
  proteins: 440
  matches: 440
  proteomes: 202
  taxa: 642
  structures: 1
  alphafold_models: 371
  domain_architectures: 2
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR008203
description: This family includes short bacterial and archaebacterial proteins thought to be antitoxin
  components of the a type II toxin-antitoxin (TA) system. This entry includes AF2212 from Archaeoglobus
  fulgidus which has sequence similarity with the AbrB superfamily of DNA-binding proteins, identified
  as antitoxins [[cite:PUB00056596],[cite:PUB00056164]]. The secondary structure of AF2212 revealed at
  least three beta-strands that are most conserved in other AbrB superfamily members [[cite:PUB00056164]].