id: Pfam:PF01956
pfam_id: PF01956
name: Integral membrane protein EMC3/TMCO1-like
short_name: EMC3_TMCO1
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01956
counters:
  proteins: 7263
  matches: 7342
  proteomes: 3937
  taxa: 9997
  structures: 16
  alphafold_models: 6324
  domain_architectures: 89
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR002809
description: This entry represents a group of eukaryotic and archaeal proteins. Eukaryotic members include
  EMC3, a subunit of the ER membrane protein complex (EMC) required for protein folding [[cite:PUB00061987]],
  and TMCO1, a ER calcium load-activated calcium channel [[cite:PUB00081416]]. Archaeal members may function
  as insertases of the archaeal plasma membrane [[cite:PUB00086930]].