id: Pfam:PF01973
pfam_id: PF01973
name: 6-hydroxymethylpterin diphosphokinase MptE-like
short_name: MptE-like
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01973
counters:
  proteins: 3321
  matches: 3325
  proteomes: 2320
  taxa: 4154
  structures: 3
  alphafold_models: 2353
  domain_architectures: 52
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR002826
description: This domain can be found in a group of proteins, including archaeal 6-hydroxymethylpterin
  diphosphokinase (6-HMDPK), known as MptE, which catalyses the formation of 6-hydroxymethyl-7,8-dihydropterin
  diphosphate (6-HMDP) from 6-HMD and ATP [[cite:PUB00061602]]. 6-HMDP is the precursor of the pterin
  containing moiety of the essential C1-carriers tetrahydrofolate and tetrahydromethanopterin. This entry
  also includes a number of uncharacterised proteins from bacteria.