id: Pfam:PF01982
pfam_id: PF01982
name: Domain of unknown function DUF120
short_name: CTP-dep_RFKase
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01982
counters:
  proteins: 682
  matches: 683
  proteomes: 657
  taxa: 1274
  structures: 8
  alphafold_models: 625
  domain_architectures: 18
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR023602
description: This domain is a CTP-dependent riboflavin kinase (RFK), found in archaea, that catalyses
  the phosphorylation of riboflavin to form flavin mononucleotide in riboflavin biosynthesis [ec:2.7.1.26].
  Its structure resembles a RIFT barrel, structurally similar to but topologically distinct from bacterial
  and eukaryotic examples. The N-terminal is a winged helix-turn-helix DNA-binding domain, and the C-terminal
  half is most similar in sequence to a group of cradle-loop barrels. [swissprot:O28174] has this domain
  attached to [pfam:PF00325].