id: Pfam:PF01983
pfam_id: PF01983
name: Guanylyl transferase CofC like
short_name: CofC
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF01983
counters:
  proteins: 3120
  matches: 3136
  proteomes: 3017
  taxa: 4189
  structures: 4
  alphafold_models: 1969
  domain_architectures: 10
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR002835
description: Coenzyme F420 is a hydride carrier cofactor that functions during methanogenesis. This family
  of proteins represents CofC, a nucleotidyl transferase that is involved in coenzyme F420 biosynthesis.
  CofC has been shown to catalyse the formation of lactyl-2-diphospho-5'-guanosine from 2-phospho-L-lactate
  and GTP [[cite:PUB00045885]].