id: Pfam:PF02082
pfam_id: PF02082
name: Iron-dependent Transcriptional regulator
short_name: Rrf2
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF02082
counters:
  proteins: 39881
  matches: 39881
  proteomes: 15706
  taxa: 22367
  structures: 21
  alphafold_models: 25715
  domain_architectures: 34
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR000944
description: Several proteins in this family form iron-sulfur clusters enabling iron dependent DNA transcription
  regulation [[cite:PUB00109206]]. The iron binding is mediated by three conserved cysteine residues.
  Members of this family can also bind O-acetyl-L-serine, [Fe-S] and nitric oxide (Matilla et. al., FEMS
  Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).