id: Pfam:PF02413
pfam_id: PF02413
name: Caudovirales tail fibre assembly protein, lambda gpK
short_name: Caudo_TAP
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF02413
counters:
  proteins: 2047
  matches: 2050
  proteomes: 872
  taxa: 1595
  structures: 1
  alphafold_models: 1042
  domain_architectures: 17
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR003458
description: This family contains bacterial and phage tail fibre assembly proteins [[cite:PUB00009480]].
  E.coli contains several members of this family although the function of these proteins is uncertain.
  Using the lambda phage members as examples, there are both gptfa and gpK tail proteins here [[cite:PUB00048232]].
  GpK forms part of the TTC or tail-tip complex that is located at the distal end of the tail. TTCs form
  the platform on which the tail-tube proteins self-assemble and are also the attachment point for fibres
  or receptor-binding proteins that mediate phage-adsorption to the surface of the host cell. TTC assembly
  starts with gpJ, which is also known as the central tail fibre and is involved in host-cell adsorption.
  It is the C-terminus of gpJ that interacts with the lamB receptor on host cells. A number of intermediates
  including gpK then interact with gpJ during tail morphogenesis [[cite:PUB00109155]].