id: Pfam:PF02578
pfam_id: PF02578
name: Multi-copper polyphenol oxidoreductase laccase
short_name: Cu-oxidase_4
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF02578
counters:
  proteins: 15217
  matches: 15292
  proteomes: 14656
  taxa: 22070
  structures: 13
  alphafold_models: 9887
  domain_architectures: 16
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR003730
description: Laccases are multi-copper oxidoreductases able to oxidise a wide variety of phenolic and
  non-phenolic compounds and are widely distributed among both prokaryotes and eukaryotes. There are two
  main active catalytic sites with conserved histidines that are capable of binding four copper atoms
  [[cite:PUB00044734]].