id: Pfam:PF02624
pfam_id: PF02624
name: YcaO cyclodehydratase, ATP-ad Mg2+-binding
short_name: YcaO
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF02624
counters:
  proteins: 8762
  matches: 8814
  proteomes: 6003
  taxa: 8712
  structures: 16
  alphafold_models: 5234
  domain_architectures: 59
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR003776
description: 'YcaO is an ATP- an Mg2+-binding protein involved in the peptidic biosynthesis of azoline.
  There three motifs involved in the binding are, in UniProtKB:P75838, 71-79: Sx3ExxER, 184-203: Sx6Ex3Qx3ExxER,
  and 286-290: RxxxE. Three slightly different functional families are represented in this family, proteins
  involved in TOMM (thiazole/oxazole-modified microcin) biogenesis, non-TOMM proteins such as UniProtKB:P75838,
  and TfuA-associated non-TOMM proteins involved in trifolitoxin biosynthesis. UniProtKB:P75838 hydrolyses
  ATP to AMP and pyrophosphate [[cite:PUB00078765]].'