id: Pfam:PF02682
pfam_id: PF02682
name: Carboxyltransferase domain, subdomain C and D
short_name: CT_C_D
seed_status: EX_DUF
characterization_status: UNSCORED
curation_status: SEEDED
source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/PF02682
counters:
  proteins: 16088
  matches: 16123
  proteomes: 11515
  taxa: 16224
  structures: 11
  alphafold_models: 9538
  domain_architectures: 83
provenance:
  snapshot_id: interpro-pfam-duf-2026-10-10
  path: data/worklists/interpro-pfam-duf-2026-10-10.json
  sha256: 17fb625876c9326ed284263a47bcd84e0d7844a31c040dc06cd2260c36f1c383
  generated_at: '2026-10-10T07:44:21.614711Z'
  source_url: https://www.ebi.ac.uk/interpro/api/entry/pfam/
interpro_id: InterPro:IPR003833
description: Urea carboxylase (UC) catalyses a two-step, ATP- and biotin-dependent carboxylation reaction
  of urea. It is composed of biotin carboxylase (BC), carboxyltransferase (CT), and biotin carboxyl carrier
  protein (BCCP) domains. The CT domain of UC consists of four subdomains, named A, B, C and D. This domain
  covers the C and D subdomains of the CT domain. This domain covers the whole length of kipI (kinase
  A inhibitor) from Bacillus subtilis [[cite:PUB00064884]]. It can also be found in S. cerevisiae urea
  amidolyase Dur1,2, which is a multifunctional biotin-dependent enzyme with domains for urea carboxylase
  and allophanate (urea carboxylate) hydrolase activity[[cite:PUB00076467]].